Characterization and fungicidal activities of four solid crystallizations of epoxiconazole

Pursuing Green and Efficient Agriculture from Molecular Assembly: A Review of Solid-State Forms on Agrochemicals

“…In the context of fungicides, the II, III, and IV crystal forms of epoxiconazole, obtained via solution-based methods, deviate from the commercially available crystal form I. 135 Employing the heat of fusion rule, it was revealed that form IV exhibited the highest activity at room temperature, thereby manifesting the highest bactericidal efficacy against Blumeriagraminis, Phakopsorhizi, and Puccinia sorghi. Supporting this perspective, the patent pertaining to the polymorphic activity of the herbicide triazole sulcotrione also corroborates this notion effectively.…”

“…Although this principle initially emerged within the realm of contact insecticides, its scope extends beyond such limitations. In the context of fungicides, the II, III, and IV crystal forms of epoxiconazole, obtained via solution-based methods, deviate from the commercially available crystal form I . Employing the heat of fusion rule, it was revealed that form IV exhibited the highest activity at room temperature, thereby manifesting the highest bactericidal efficacy against Blumeriagraminis , Phakopsorhizi , and Puccinia sorghi .…”

Construction and application of a qualitative and quantitative analysis system of three boscalid polymorphs based on solid-state analytical methods and chemometric tools

“…in the production and storage process, the crystalline form of an agrochemical might be changed, which results in the phase purity of the final product not being up to standard. 9 Thus, constructing and applying a qualitative and quantitative analysis system to detect and quantify the different polymorphs in products is necessary for producers to control the production of qualified agrochemicals. Some solid-state analytical methods (including vibrational spectroscopies, X-ray powder diffraction, differential scanning calorimetry, solid-state NMR spectrometry, etc.)…”