Characterization and Identification of Erysipelothrix rhusiopathiae Isolated from an Unnatural Host, a Cat, with a Clinical Manifestation of Depression

Lee, Jin Ju; Kim, Dong Hyeok; Lim, Jeong Ju; Kim, Dae Geun; Chang, Hong; Lee, Hu Jang; Kim, Sang Hun; Rhee, Man Hee; Endale, Mehari; Imada, Yumiko; Kim, Ok Jin; Kim, Suk

doi:10.1292/jvms.10-0248

Cited by 7 publications

(4 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…strain 2 (serotype 18) [1,2]. E. rhusiopathiae is a small, Gram-positive, slender, straight, rod-shaped bacterium that causes erysipelas in swine and many other animals [3][4][5][6][7][8]. Swine erysipelas can cause pyrexia, lameness, characteristic diamond skin lesions, and even sudden death in growing and adult swine [9].…”

Section: Introductionmentioning

confidence: 99%

Characterization of Erysipelothrix rhusiopathiae Isolates from Diseased Pigs in 15 Chinese Provinces from 2012 to 2018

Zhao

et al. 2021

Microorganisms

View full text Add to dashboard Cite

Erysipelothrix rhusiopathiae can cause erysipelas in animals and erysipeloid in humans. Since its recurrence in 2012, swine erysipelas has caused serious losses within the pig industry in China. The aim of this study was to perform multilocus sequence typing and understand the virulence and antimicrobial susceptibility of E. rhusiopathiae isolates in China. Multilocus sequence typing (MLST) of a total of 120 strains was performed, and as a result, three different sequence types were identified, of which ST48 was the main one. Five isolates of each MLST type were randomly selected to be used to challenge mice. ST48 was associated with a higher virulence. Antimicrobial susceptibility was tested using a microdilution technique and, to analyze the resistance mechanism, six strains were selected for genome sequencing. A comparison of the six genomes indicated the presence of a suspected macrolide resistance gene, namely, Erm(A)-like, in erythromycin-resistant strains, which increased the minimum inhibitory concentration (MIC) of erythromycin against E. coli C600 at least four-fold. In addition, three mutations (gyrA86T-I, gyrA90D-N, and parC81S-I) were observed in the quinolone resistance-determining regions (QRDRs) of gyrA and parC in quinolone-resistant strains. After the gyrA gene with the 86T-I mutation or the parC gene with the 81S-I mutation was transfected into E. coli C600, the MIC of enrofloxacin against this strain increased at least two-fold. Our findings provide a theoretical basis for developing antibacterial drugs and may contribute to the clinical prevention and control of E. rhusiopathiae.

show abstract

Section: Introductionmentioning

confidence: 99%

Characterization of Erysipelothrix rhusiopathiae Isolates from Diseased Pigs in 15 Chinese Provinces from 2012 to 2018

Zhao

et al. 2021

Microorganisms

View full text Add to dashboard Cite

show abstract

“…Erysipelothrix rhusiopathiae, belonging to the family Erysipelotrichac eae, is a non-motile, Gram-positive, nonsporulating, non-acid-fast organism distributed worldwide affecting wide variety of vertebrate and invert ebrate species including man (Reboli and Farrar, 1989). Organisms in many occasions harbour by pigs in lymph nodes and shed along with feces, urine, saliva and nasal secretions (Lee et al, 2011). Affected pigs manifest the disease as (i) acute septic form, (ii) subacute urticarial form marked by reddis h-purple rhomboid spots or "diamonds" in the skin, (iii) joint or art hritic form, and (iv) chronic cardiac form (endocarditis) (Reboli and Farrar, 1989).Various predisposing factors, change of environmental conditions and parasitic infestation lead to *Corresponding author.…”

Section: Introductionmentioning

confidence: 99%

Seasonal emergence of swine erysipelas in hilly state Nagaland, Northeast India

Barman¹,

Borkotoky²,

Borah³

et al. 2016

Afr. J. Microbiol. Res.

View full text Add to dashboard Cite

Seasonal outbreaks of swine erysipelas have been reported in back yard pig farms in the Phek district of Nagaland, India. The alpha haemolytic isolate of Erysipelothrix rhusiopathi ae was recovered on blood agar from the clinical samples. The organism s were confirmed microscopically, biochemical analysi s as well as by polymerase chain reaction (PCR) amplification of 16S rRNA gene and sequence analysi s. These Nagaland isolates (KT160358, KT160359) were closely related to the type spp. E. rhusiopathiae in phylogenetic analysi s and form s the same clad with Chineese isolates of swine and murine origin indicating an epidemiological link. The isolates were found to be most sensitive to oxytetracycline and responded to treatment. Swine erysipelas occurred in Phek district in a season due to sudden change of weather and temperature. Pigs exposed to such predi sposing factors probably favoured to propagation of already persi sted organi sm s in pigs. Thi s i s the first confirmed case of E. rhusiopathiae infection from the NE states of Nagaland, India.

show abstract

“…Natural infection in a cat indicated the possible epidemiological significance and implication as a potential source of infection to other animals and humans. 87 Cat bite has caused human infection due to this bacterium.…”

mentioning

confidence: 99%

Zoonotic Bacteria Associated with Cats

Hariharan¹,

Hariharan²

2017

Vet Med Open J

View full text Add to dashboard Cite

CitationHariharan H, Hariharan SH. Zoonotic bacteria associated with cats. Vet Med Open J. 2017; 2(3): 68-75. doi: 10.17140/VMOJ-2-118 ABSTRACT Background: There are several bacterial pathogens, including Bartonella, and Pasteurella that have been known to cause human infections from contact with cats. Recently, certain bacteria have emerged as causes of infection in cats, resulting in transmission to humans. Objectives: This review presents updated information on the zoonotic bacterial pathogens associated with cats, with special emphasis on recent reports. Results: Presently, an increase in the incidence of cat-associated Yersinia pestis human infections in the western USA has become a concern. In addition, infections due to Mycobacterium bovis, and Brucella abortus, are being recognized. Also, a number of human infections due to Campylobacter, Helicobacter, and Salmonella from cats have been documented worldwide. In addition, spread of bacteria resistant to antimicrobial drugs from cats is becoming a possibility. Conclusion: Updated information shows that more zoonotic bacteria than previously recognized are associated with cats worldwide. Immunocompromised persons and young children are particularly at a risk of developing infection from household cats which are allowed to roam around outdoors. It is important to incorporate environmental and animal contact considerations into patient care. With proper handling and precautions, cats can help establish valuable humananimal bonds.

show abstract

Characterization and Identification of Erysipelothrix rhusiopathiae Isolated from an Unnatural Host, a Cat, with a Clinical Manifestation of Depression

Cited by 7 publications

References 17 publications

Characterization of Erysipelothrix rhusiopathiae Isolates from Diseased Pigs in 15 Chinese Provinces from 2012 to 2018

Characterization of Erysipelothrix rhusiopathiae Isolates from Diseased Pigs in 15 Chinese Provinces from 2012 to 2018

Seasonal emergence of swine erysipelas in hilly state Nagaland, Northeast India

Zoonotic Bacteria Associated with Cats

Contact Info

Product

Resources

About