Characterization and identification of gastric hyperplastic polyps and adenomas by confocal laser endomicroscopy

Li, Wenbo; Zuo, Xu; Zuo, Fang; Gu, Xiaomeng; Yu, Tao; Zhao, Yijun; Zhang, Tingguo; Zhang, Jianping; Li, Yanqing

doi:10.1007/s00464-009-0608-y

Cited by 44 publications

(39 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In a study carried out by Li et al (13), it was reported that the most common location for gastric polyps was the antrum, accounting for 40.7% of all gastric polyps. Similarly, in our study, the antrum (41.5%) was the most common location for the gastric polyps, followed by the corpus (35.4%).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of gastric polyps detected by endoscopy: A single-center study of a four-year experience in Turkey

Atalay

Solakoğlu²,

Sarı³

et al. 2020

Turk J Gastroenterol

View full text Add to dashboard Cite

Background/Aims: The aim of this study was to evaluate the gastric polyps detected by endoscopy in our institution with respect to their frequency, size, anatomic location, presence of dysplasia, and histopathologic features. Materials and Methods: Records of a total of 14,240 patients who underwent endoscopy between January 2008 and January 2012 were reviewed retrospectively. Of the 14,240 patients, 174 determined to have at least 1 histopathologically proven polyp were included in the study. Results: Three hundred eleven gastric polyps were found in 174/14,240 (1.2%) patients (1.79 polyps per patient). Gastric polyps were found most commonly in the antrum (41.5%). Of all gastric polyps, 189 (60.8%) were less than 1 cm. Histopathologically, the most common polyp type was hyperplastic (n: 261, 83.9%), followed by adenomatous (n: 23, 7.4%). Eight (34.8%) of the adenomatous polyps showed dysplasia, and in 4 (17.4%) of these cases, the dysplasia was high-grade. Nineteen (6.1%) of all gastric polyps were identified to be fundic gland polyps. Conclusion: According to this study from Turkey, the majority of polyps detected by endoscopy was solitary, smaller than 1 cm, and found in the antrum; furthermore, the most common type was a hyperplastic polyp.

show abstract

Section: Discussionmentioning

confidence: 99%

Evaluation of gastric polyps detected by endoscopy: A single-center study of a four-year experience in Turkey

Atalay

Solakoğlu²,

Sarı³

et al. 2020

Turk J Gastroenterol

View full text Add to dashboard Cite

show abstract

“…Endomicroscopy showed a high accuracy for this differentiation [38], again supporting its use for immediate resection of suspicious lesions. Early trials on gastric cancer have used acriflavine-augmented ex vivo confocal microscopy on biopsy specimens with good accuracy rates [39].…”

Section: Endomicroscopy Of Gastricmentioning

confidence: 60%

Confocal Laser Endomicroscopy: Applications in Clinical and Translational Science—A Comprehensive Review

Goetz

2012

ISRN Pathology

View full text Add to dashboard Cite

Confocal laser endomicroscopy (CLE) is a novel tool in the endoscopist's armamentarium. It allows on-site histological information. The ability of gastroenterologists to interpret such microscopic information has been demonstrated in multiple studies from the upper and lower gastrointestinal tract. Recently, the field of application has expanded to provide hepatobiliary and intra-abdominal CLE imaging. CLE allows "smart," targeted biopsies and is able to guide endoscopic interventions. But CLE is also translational in its approach and permits functional imaging that significantly impacts on our understanding of gastrointestinal diseases. Molecular imaging with CLE allows detection and characterization of lesions and may even be used for prediction of response to targeted therapy. This paper provides a comprehensive review over current applications of CLE in clinical applications and translational science.

show abstract

“…In a study of 87 gastric polyps, the overall accuracy of CLE diagnosis of hyperplastic and adenomatous polyps during endoscopy was 90% and the overall accuracy of differentiating gastric hyperplastic polyps and adenomas by CLE after endoscopy was 97%. 36 …”

Section: Gastric Intestinal Metaplasia Gastric Polyps and Gastric Camentioning

confidence: 99%

Status of confocal laser endomicroscopy in gastrointestinal disease

Humphris

Swartz

Egan

et al. 2012

View full text Add to dashboard Cite

Confocal laser endomicroscopy (CLE) is an advanced imaging technique which combines conventional white light endoscopy (WLE) with an integrated or probe based confocal microscope. This allows microscopic examination of the surface epithelium and in vivo diagnosis during endoscopy. Established CLE applications include the diagnosis of Barrett's oesophagus, gastric intestinal metaplasia, coeliac disease and microscopic colitis. CLE can differentiate hyperplastic from adenomatous polyps in the colon and may obviate the need to biopsy all polyps at endoscopy. CLE is particularly helpful in surveillance endoscopy in inflammatory bowel disease where it has been shown to reduce the number of biopsies required and improve the detection of dysplasia. The future of CLE may be with new contrast agents to allow for molecular tagging and improved endoscopic diagnoses. The aim of this review is to describe the technology and techniques involved in CLE, and discuss the evolving applications in obtaining "virtual biopsy" throughout the GI tract.

show abstract

Characterization and identification of gastric hyperplastic polyps and adenomas by confocal laser endomicroscopy

Abstract: This study characterized confocal images of gastric hyperplastic polyps and adenomas as well as the high accuracy of differentiating hyperplastic polyps and adenomas using CLE.

Cited by 44 publications

References 24 publications

Evaluation of gastric polyps detected by endoscopy: A single-center study of a four-year experience in Turkey

Evaluation of gastric polyps detected by endoscopy: A single-center study of a four-year experience in Turkey

Confocal Laser Endomicroscopy: Applications in Clinical and Translational Science—A Comprehensive Review

Status of confocal laser endomicroscopy in gastrointestinal disease

Contact Info

Product

Resources

About