2013
DOI: 10.1016/j.ijbiomac.2012.09.005
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Characterization and in vitro antitumor activity of polysaccharides from the mycelium of Sarcodon aspratus

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Cited by 63 publications
(25 citation statements)
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“…Interestingly, the active constituents that are involved in these effects of mushroom are considered to be polysaccharides, which can induce tumor cell death in several cancer types [1,31]. Therefore, in the present study we characterized the main constituents of PAP using precolumn PMP derivatization HPLC and evaluated their antiproliferative and pro-apoptotic effects on human colorectal carcinoma LoVo cells.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Interestingly, the active constituents that are involved in these effects of mushroom are considered to be polysaccharides, which can induce tumor cell death in several cancer types [1,31]. Therefore, in the present study we characterized the main constituents of PAP using precolumn PMP derivatization HPLC and evaluated their antiproliferative and pro-apoptotic effects on human colorectal carcinoma LoVo cells.…”
Section: Discussionmentioning
confidence: 99%
“…Medicinal or edible mushroom consumption is associated with the improvement of human health, especially for cancer prevention [1,31]. Interestingly, the active constituents that are involved in these effects of mushroom are considered to be polysaccharides, which can induce tumor cell death in several cancer types [1,31].…”
Section: Discussionmentioning
confidence: 99%
“…Absorption peaks were also observed at 1597 cm −1 and 1413 cm −1 which can be attributed to the carboxyl groups of uronic acid residues in the gum polysaccharide [1]. The wave number between 950 cm −1 and 1200 cm −1 is often regarded as the fingerprint region as it allows the identification of major chemical groups in polysaccharides [14]. Also the strong absorption at 1014 cm −1 indicated the stretching vibration of the C-N [31].…”
Section: Physicochemical Propertiesmentioning
confidence: 99%
“…However, their functional and rheological properties often depend on their monosaccharide composition, type of linkage [11,12]. In recent years, natural polysaccharides have received increased interest for the prevention and treatment of various diseases caused by oxidative damage [12] such as anticancer [13,14], immunomodulation [15], antioxidant and anti-inflammatory properties [12,16]. Therefore, studies on the application of these natural polysaccharides as antioxidants have become highly valuable.…”
Section: Introductionmentioning
confidence: 99%
“…Mushrooms have been known for their medicinal and culinary use for thousands of years (Chen et al, 2013). Mushrooms were consumed by people of eastern Asia for their culinary and medicinal properties since ancient times.…”
Section: Medicinal Mushroomsmentioning
confidence: 99%