Characterization and prognostic significance of silent myocardial ischemia on predischarge electrocardiographic monitoring in unselected patients with myocardial infarction

Petretta, Mario; Bonaduce, Domenico; Bianchi, Valter; Vitagliano, Giancarlo; Conforti, Gabriele; Rotondi, Francesco; Themistoclakis, Sakis; Morgano, G

doi:10.1016/0002-9149(92)90145-o

Cited by 34 publications

(28 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…33,34 Silent ischemia in the postinfarct phase does predict cardiac events when revascularization is included as an event, and although the prognostic importance of silent ischemia in the postinfarct phase is attenuated during long-term follow-up, the presence of silent ischemia remains predictive of all cardiac events up to 5 years after the index infarct. 35 When subjected to multivariate analysis, ambulatory ischemia fails to outperform clinical indices such as Killip class 36 in predicting acute events. The addition of other variables such as heart rate variability and the detection of ventricular tachycardia to silent ischemia to create a combined index of abnormal ambulatory ECG responses can improve the sensitivity and predictive value of the test.…”

Section: Patients Who Have Had MImentioning

confidence: 99%

Silent Myocardial Ischemia

2003

View full text Add to dashboard Cite

Section: Patients Who Have Had MImentioning

confidence: 99%

Silent Myocardial Ischemia

2003

View full text Add to dashboard Cite

“…In previous studies it has been proposed that TMI detected within a few days after AMI may predict an adverse short- and medium-term outlook for death or reinfarction [1, 5, 6, 11, 23]. In-hospital mortality rates after AMI range from 10 to 15% and it seems reasonable to assume that the earlier after the index event Holter monitoring is performed, the more likely patients at heightened risk of future hard endpoints may be identified.…”

Section: Discussionmentioning

confidence: 99%

“…Episodes of transient myocardial ischemia (TMI) can be detected in 14–42% of patients recovering from acute myocardial infarction (AMI), if ambulatory monitoring is performed <3 weeks after the index event [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11]. From prognostic studies available we know that TMI may be associated with an adverse clinical outcome [1, 2, 3, 5, 6, 7, 8, 10, 11].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Serial Holter ST-Segment Monitoring after First Acute Myocardial Infarction

Mickley

Nielsen²,

Berning³

et al. 1998

Cardiology

View full text Add to dashboard Cite

Based on serial Holter monitoring performed 7 times within 3 years after a first acute myocardial infarction, we assessed the prevalence, variability and long-term clinical importance of transient myocardial ischemia (TMI) defined as episodes of ambulatory ST-segment depression. In all, 121 consecutive male patients <70 years old were studied. The prevalence of TMI on different Holter recordings varied around 20% ranging between 18 and 27%. Fifty-five of the patients (46%) had TMI on at least 1 of the 7 Holter recordings. Considerable variability was found within and between patients for the presence of TMI. No high-risk group for cardiac death, nonfatal reinfarction or coronary revascularization during up to 10 years of follow-up could be identified by the detection of TMI. From these results we conclude that a routine search for TMI on serial Holter monitoring cannot be recommended in male survivors of an uncomplicated first acute myocardial infarction.

show abstract

“…[1][2][3] One of the earliest investigations addressing the prevalence and significance of silent myocardial ischemia in asymptomatic subjects is the United States Air Force study, 4 conducted in 1,390 men, 111 of whom had positive exercise tests. Thirty-four of these 111 (about 2.5% of the total) had coronary artery lesions of at least 50% stenosis.…”

mentioning

confidence: 99%