Characterization, Antibiofilm, and Mechanism of Action of Novel PEG-Stabilized Lipid Nanoparticles Loaded with Terpinen-4-ol

Sun, Liming; Zhang, Chen-lu; Li, Ping

doi:10.1021/jf3010405

Cited by 65 publications

(29 citation statements)

References 33 publications

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“…Recently, Sun et al [99] reported the antibiofilm activity of terpinen-4-ol-loaded lipid nanoparticles against C. albicans biofilms. The compound used (10 μ g/mL) eradicated formed biofilms [99].…”

Section: Antibiofilm Strategiesmentioning

confidence: 99%

Innovative Strategies to Overcome Biofilm Resistance

Taraszkiewicz

Fila

Grinholc

et al. 2013

BioMed Research International

166

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We review the recent literature concerning the efficiency of antimicrobial photodynamic inactivation toward various microbial species in planktonic and biofilm cultures. The review is mainly focused on biofilm-growing microrganisms because this form of growth poses a threat to chronically infected or immunocompromised patients and is difficult to eradicate from medical devices. We discuss the biofilm formation process and mechanisms of its increased resistance to various antimicrobials. We present, based on data in the literature, strategies for overcoming the problem of biofilm resistance. Factors that have potential for use in increasing the efficiency of the killing of biofilm-forming bacteria include plant extracts, enzymes that disturb the biofilm structure, and other nonenzymatic molecules. We propose combining antimicrobial photodynamic therapy with various antimicrobial and antibiofilm approaches to obtain a synergistic effect to permit efficient microbial growth control at low photosensitizer doses.

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Section: Antibiofilm Strategiesmentioning

confidence: 99%

Innovative Strategies to Overcome Biofilm Resistance

Taraszkiewicz

Fila

Grinholc

et al. 2013

BioMed Research International

166

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“…e compound used (10 g/mL) eradicated formed bio�lms [99]. Finally, the antibio�lm activity of povidone-iodine (PVP-I) was con�rmed by Hosaka et al [100] against Porphyromonas gingivalis and Fusobacterium nucleatum bio�lms.…”

Section: �Ther Bio�lm-�isrupting Factorsmentioning

confidence: 94%

“…Recently, Sun et al [99] reported the antibio�lm activity of terpinen-4-ol-loaded lipid nanoparticles against C. albicans bio�lms. e compound used (10 g/mL) eradicated formed bio�lms [99].…”

Section: �Ther Bio�lm-�isrupting Factorsmentioning

confidence: 99%

Antimicrobial, Antimycobacterial and Antibiofi lm Properties of Couroupita guianensis Aubl. Fruit Extract

Sayen¹

2014

Biofilm Control and Antimicrobial Agents

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We review the recent literature concerning the efficiency of antimicrobial photodynamic inactivation toward various microbial species in planktonic and bio�lm cultures. e review is mainly focused on bio�lm-growing microrganisms because this form of growth poses a threat to chronically infected or immunocompromised patients and is difficult to eradicate from medical devices. We discuss the bio�lm formation process and mechanisms of its increased resistance to various antimicrobials. We present, based on data in the literature, strategies for overcoming the problem of bio�lm resistance. �actors that have potential for use in increasing the efficiency of the killing of bio�lm-forming bacteria include plant extracts, enzymes that disturb the bio�lm structure, and other nonenzymatic molecules. We propose combining antimicrobial photodynamic therapy with various antimicrobial and antibio�lm approaches to obtain a synergistic effect to permit efficient microbial growth control at low photosensitizer doses.

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“…Likewise terpinen-4-ol-loaded lipid nanoparticles were observed to eradicate C. albicans biofilms [35]. …”

Section: Antibiofilm Treatmentsmentioning

confidence: 99%

Antibiofilm Treatment for Onychomycosis and Chronic Fungal Infections

Gupta

Carviel

Shear

2017

Skin Appendage Disord

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Onychomycosis is a difficult-to-treat chronic fungal infection of the nail. The chronic nature of onychomycosis, with relevance to current treatment practices, could be attributed to host anergy, development of increased virulence in causal agents (multidrug resistance efflux pump), and biofilms. Biofilms must be disrupted prior to antifungal treatment suggesting the necessity of combination treatment. Once the biofilm has been disrupted, further techniques in addition to antifungal usage are suggested to ensure a positive prognosis including use of antimicrobial photodynamic therapy or low-frequency surface acoustic waves. Overall, with continued success in developing antibiofilm treatment for bacterial and yeast pathogens, therapy can be more quickly expanded to dermatophytes. With a rise in predisposing factors, it is important to preemptively address treatment for this disease with continued investigation into antibiofilm therapy including optimal treatment combinations and dosages targeted specifically at dermatophytes.

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Characterization, Antibiofilm, and Mechanism of Action of Novel PEG-Stabilized Lipid Nanoparticles Loaded with Terpinen-4-ol

Cited by 65 publications

References 33 publications

Innovative Strategies to Overcome Biofilm Resistance

Innovative Strategies to Overcome Biofilm Resistance

Antimicrobial, Antimycobacterial and Antibiofi lm Properties of Couroupita guianensis Aubl. Fruit Extract

Antibiofilm Treatment for Onychomycosis and Chronic Fungal Infections

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