Characterization-based Q–Q plots for testing multinormality

Liang, Jiajuan; Pan, William; Yang, Zhen

doi:10.1016/j.spl.2004.10.002

Cited by 28 publications

(18 citation statements)

References 11 publications

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“…Like in other cancers [50,53,73,97,104,121,134,138,160,182], levels of sFas and sFasL were found to be elevated in serum of patients with lung cancer as compared with healthy individuals [161]. Concerning therapy response during chemotherapy, Fas in serum of SCLC patients with complete response was lower than in non-responsive patients [161].…”

Section: Fas-receptor and Fas-ligandmentioning

confidence: 78%

Circulating apoptotic markers in the management of non-small cell lung cancer

Holdenrieder

Stieber

2010

CBM

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The dysregulation of proliferating and apoptotic processes is a common feature in cancerogenesis. Thus, apoptotic products released into blood circulation are suggested as promising markers for the early cancer detection. However though sensitive assays are available, the lack of organ- and tumor-specificity limits the usefulness of most apoptotic parameters for screening purposes. However, they seem to be valuable for the prognosis and the prediction of response to systemic chemo- or radiotherapy in cancer disease.Here, the relevance of diverse circulating apoptotic markers is reviewed for the clinical management of patients with lung cancer. Among those promising markers are ligands and receptors of the FAS-system, members of the intracellular caspase cascade, cleaved apoptosis substrates such as cytokeratines, nucleosomal DNA, and apoptosis modulators like survivin. The review discusses their role for diagnosis, prognosis and therapy monitoring of lung cancer disease.

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Section: Fas-receptor and Fas-ligandmentioning

confidence: 78%

Circulating apoptotic markers in the management of non-small cell lung cancer

Holdenrieder

Stieber

2010

CBM

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“…For further investigating whether the distribution of average chemical shifts of six nuclei in five kinds of protein super secondary structures are independent of one another. Firstly, the Q-Q plot in statistics is an exploratory graphical device used to check the validity of a normal distributional assumption for a dataset (Liang et al, 2004). The results demonstrated that the CSs six nuclei obey normal distribution (see Supplementary material).…”

Section: Resultsmentioning

confidence: 99%

Identify five kinds of simple super-secondary structures with quadratic discriminant algorithm based on the chemical shifts

Kou

Feng

2015

Journal of Theoretical Biology

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“…This provides quite strong evidence that multi-collinearity is not present within the dataset. A Q-Q plot (Liang et al 2004) suggests that the normality assumption is complied with. Figure 1 presents, however, a scatterplot of the squared residuals relative to the unstandardized predicted values, which suggests that the assumption of homoscedasticity is being violated.…”

Section: Diagnostic Testingmentioning

confidence: 98%

The impact of potential Brexit scenarios on German car exports to the UK: an application of the gravity model

2018

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The objective is to forecast the impact of potential Brexit scenarios on the export volume of passenger cars from Germany to the UK. Based on Germany's total export volume of passenger cars, a double-logarithmic gravity model is specified and estimated using Ordinary Least Squares (OLS) regression. The final estimated model has strong explanatory power, with all variables significant at the 5% level. This is used for forecasting future export volumes under different Brexit scenarios. Diagnostic tests suggest that the model is robust and efficient. All tested Brexit scenarios are found to negatively impact passenger cars export volumes from Germany to the UK. The level of tariffs is found to have the most significant effect, but lower GDP due to Brexit is forecast to offset the benefits of trading with lower tariffs. The most pessimistic scenario for 2030 forecasts is a reduction of 15.4% compared to the 'no Brexit' base-case scenario.

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Characterization-based Q–Q plots for testing multinormality

Cited by 28 publications

References 11 publications

Circulating apoptotic markers in the management of non-small cell lung cancer

Circulating apoptotic markers in the management of non-small cell lung cancer

Identify five kinds of simple super-secondary structures with quadratic discriminant algorithm based on the chemical shifts

The impact of potential Brexit scenarios on German car exports to the UK: an application of the gravity model

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