Characterization of a Cellulose Trisphenylcarbamate/1-Octyl-3-methylimidazolium Tetrafluoroborate Mixture as GC Stationary Phase: Thermodynamic Parameters and LSER Methodology

Shi, Jie‐Hua; Xu, Shui-xing; Jia, Qi; Yan, Xiu‐Ping

doi:10.1007/s10337-013-2495-6

Cited by 7 publications

(4 citation statements)

References 23 publications

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“…The thickness of NaCl-TPP coating from the different segments were about 0.7–0.8 µm respectively attesting the thickness uniformity of the entire length of the column. Furthermore, the TPP layer thickness was about 0.16 µm calculated by the empirical formula, df=(dc/c)/400, where dc is the capillary inner diameter(mm) and c is the concentration of the stationary phase(%,w/v) ( Shi et al, 2012 ; Shi et al, 2013 ).…”

Section: Resultsmentioning

confidence: 99%

Capillary Gas Chromatographic Separation Performances of a Tetraphenyl Porphyrin Stationary Phase

et al. 2022

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Tetraphenyl porphyrin (TPP) has enormous potential for use as gas chromatography stationary phases because it has a distinctive extended π–π conjugated coplanar structure and a range of interesting properties such as a good solubility in dichloromethane, high melting point, and good thermal stability. In this work, a TPP column was successfully prepared using a static method. The column was nonpolar and had a high efficiency. The chromatographic selectivity of the TPP column was assessed. The TPP column showed superiority retention and higher resolution for alicyclic, aromatic molecules through ring matching and π-π stacking interaction comparable to HP-5MS column. The unique mechanisms through which the TPP column retained polychlorinated biphenyls allowed the peak pair of 2,2ʹ,5-trichlorobiphenyl and 4,4ʹ-dichlorobiphenyl to be resolved better on the TPP column than the HP-5MS column. The TPP column was thermally stable even at 260°C for 2 h and gave results of a high degree of precision (run-to-run and column-to-column) with relative standard deviations <0.05% and <4.96%, respectively. The results indicated that porphyrin derivatives will be useful gas chromatography stationary phases.

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Section: Resultsmentioning

confidence: 99%

Capillary Gas Chromatographic Separation Performances of a Tetraphenyl Porphyrin Stationary Phase

et al. 2022

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“…The relationship between the retention factor ( k ) or separation factor ( α ) and the column temperature ( T ) during chromatographic chiral separation process can be described by the Gibbs–Holmholtz and van't Hoff equations as follows 28,29 :

\ln k = - \frac{normalΔ H}{RT} + \frac{normalΔ S}{R} + \ln ϕ,

\ln α = - \frac{normalΔ ((), normalΔ H)}{RT} + \frac{normalΔ ((), normalΔ S)}{R},

normalΔ G = normalΔ H - T normalΔ S,

where k is the capacity factor of enantiomers and α is the separation factor between ( R )‐isomer and ( S )‐isomer. Δ G , Δ H , and Δ S represent the Gibbs free energy change, the enthalpy change, and the entropy change, respectively.…”

Section: Resultsmentioning

confidence: 99%

“…The different hydro-organic mobile phases made up with water and acetonitrile were tested, and the results were summarized in Table S3. The results indicated that the values of k and α of these enantiomers gradually increased with a decrease of acetonitrile content in mobile phase containing HP-β-CD, indicating that the proportion of acetonitrile in the mobile phase obviously affected the partition coefficient of each enantiomer between stationary phase (C 18 column) and mobile phase 28,29 and thus affected the k value of each enantiomer. Combined with the influence of HP-β-CD on the chromatographic retention, it can be inferred that the retention behavior of each enantiomer is driven by its partition coefficient between the mobile and stationary phases and its complexation with cyclodextrins.…”

Section: Influence Of Proportion Of Acetonitrilementioning

confidence: 98%

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Enantioseparation of mandelic acid and substituted derivatives by high‐performance liquid chromatography with hydroxypropyl‐β‐cyclodextrin as chiral mobile additive and evaluation of inclusion complexes by molecular dynamics

et al. 2021

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The enantioseparation and resolution mechanism of mandelic acid (MA), 4-methoxymandelic acid (MMA), and 4-propoxymandelic acid (PMA) were investigated by reversed-phase high-performance liquid chromatography (HPLC) with 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) as a chiral mobilephase additive and molecular dynamics simulation. The suitable chromatographic conditions for the enantioseparation of MA, MMA, and PMA were obtained. Under the selected chromatographic conditions, these enantiomers could achieve baseline separation. The results of thermodynamic parameter analysis revealed that the main driven forces for the enantioseparation of MA, MMA, and PMA could be van der Waals forces and hydrogen-bonding interactions and the chromatographic retention of these chiral compounds was an enthalpy-driven process. The results of the molecular simulation revealed that their chiral resolution mechanism on HP-β-CD was responsible for the formation of inclusion complexes of enantiomers with HP-β-CD with different conformations and binding energies. And the binding energy of HP-β-CD with (S)-isomer was larger than that with (R)-isomer, which is consistent with the experimental results of the first elution of (S)-isomer. Additionally, it is also confirmed that the interaction energies included the van der Waals energy (ΔE vdw ), electrostatic energy (ΔE elec ), polar solvation energy, and SASA energy (ΔE sasa ), and the separation factor (α) was closely connected with the disparity in the binding energies of optical isomers and HP-β-CD complexes. Meanwhile, from molecular dynamics simulation, it can be found that the Δ (ΔE binding ), (Δ(ΔE binding ) = ΔE binding,R À ΔE binding,S ) value was in order of MA-HP-β-CD complex > MMA-HP-β-CD complex > PMA-HP-β-CD complex, which was consistent with the order of Δ(ΔG) values obtained from van't Hoff plot. This indicated that the molecular dynamics simulation has predictive function for chiral resolution.

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Electrokinetic chromatographic characterization of novel catanionic surfactants vesicle as pseudostationary phase

Lü

Cao

et al. 2014

Electrophoresis

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A novel catanionic surfactants vesicle system composed of octyltriethylammonium bromide/ sodium dodecyl benzene sulfonate (C8 NE3 Br/SDBS) has been developed as pseudostationary phase (PSP) in EKC. The C8 NE3 Br/SDBS system possesses a large vesicle phase region and none of agglomeration phenomena appeared while mixing cationic and anionic surfactants at any molar ratio. Electrophoretic and chromatographic parameters including elution window, hydrophobic selectivity, polar group selectivity, and shape selectivity were characterized using the vesicle at molar ratio of C8 NE3 Br to SDBS of 3:7 as PSP. Compared with SDS micelles, the vesicle PSP possessed a wider elution window and a better selectivity. The retention behavior and selectivity differences between the novel vesicle and SDS micelles were evaluated through linear solvation energy relationship (LSER) analysis. Though the cohesiveness and the hydrogen bond acidity have greatest influences on the solutes retention and selectivity in both the vesicle and SDS micelle, the vesicle PSP demonstrated a higher hydrophobicity and a lower hydrogen bonding donating capability owing to compact bilayer structure of vesicle. Additionally, the vesicle system had a stronger hydrogen bond accepting capability than SDS micelle. Consequently, according to LSER analysis, the bigger coefficients for v, b, and a revealed the vesicle PSP had a better separation selectivity than conventional SDS micelle.

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Characterization of a Cellulose Trisphenylcarbamate/1-Octyl-3-methylimidazolium Tetrafluoroborate Mixture as GC Stationary Phase: Thermodynamic Parameters and LSER Methodology

Cited by 7 publications

References 23 publications

Capillary Gas Chromatographic Separation Performances of a Tetraphenyl Porphyrin Stationary Phase

Capillary Gas Chromatographic Separation Performances of a Tetraphenyl Porphyrin Stationary Phase

Enantioseparation of mandelic acid and substituted derivatives by high‐performance liquid chromatography with hydroxypropyl‐β‐cyclodextrin as chiral mobile additive and evaluation of inclusion complexes by molecular dynamics

Electrokinetic chromatographic characterization of novel catanionic surfactants vesicle as pseudostationary phase

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