2023
DOI: 10.1002/lio2.1067
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Characterization of a chronic cough in cerebellar ataxia, neuropathy, vestibular areflexia syndrome

Abstract: Objectives Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is a common cause of late‐onset ataxia that often presents with chronic cough. This study is the first to characterize the CANVAS cough both objectively and subjectively. Methods A cross‐sectional study of 13 patients was conducted. Medical records and available esophagram, modified barium swallow study, esophageal manometry, and video laryngostroboscopy data were reviewed. Leicester cough questionnaire (LCQ) and Eating Ass… Show more

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Cited by 7 publications
(1 citation statement)
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“…Dysautonomia is often a feature of MSAc [59 & ] and may be seen in SCA1, 2, 3 [64], 27B [65], FA [66] and CANVAS [67,68] amongst others. In the appropriate clinical context, enquiring regarding a chronic cough may help in the diagnosis of CANVAS as this can precede other symptoms by many years to decades [69,70].…”
Section: Identifying Extra-sensory Involvementmentioning
confidence: 99%
“…Dysautonomia is often a feature of MSAc [59 & ] and may be seen in SCA1, 2, 3 [64], 27B [65], FA [66] and CANVAS [67,68] amongst others. In the appropriate clinical context, enquiring regarding a chronic cough may help in the diagnosis of CANVAS as this can precede other symptoms by many years to decades [69,70].…”
Section: Identifying Extra-sensory Involvementmentioning
confidence: 99%