Fluid injection in a porous medium is the underlying mechanism for many applications in the fields of groundwater hydraulics, hydrology and hydrogeology, and geo-environmental engineering and in the oil and gas industry. Fluid flow experiments in porous media with a viscous fluid at varying injection rates were conducted in a modified Hele-Shaw setup. The granular media were three-dimensional bio-cemented sands of various grain sizes across various cementation levels, generating a matrix of various hydraulic conductivities, porosities, and strengths. The fluid injection experiments showed that a cavity-like fracture developed, which transitioned to crack-like fractures at higher cementation levels (hence, higher strength). As the flow rate increased, less infiltration was evident and higher breakdown pressure was observed, with propagation pressure reducing to zero. It was harder to induce an opening in cemented specimens with higher hydraulic conductivity and a larger pore network despite their lower strength due to excessive infiltration dominance, which inhibited the build-up of pressure required to generate a fracture. The results of this study suggest that, when designing fluid injection programs, the combined effects of hydraulic conductivity and strength need to be carefully considered.