Characterization of a new stationary phase based on microwave immobilized polybutadiene on titanium oxide-modified silica

Application of liquid phase deposited titania nanoparticles on silica spheres to phosphopeptide enrichment and high performance liquid chromatography packings

“…For example, titania-silica composite prepared by co-precipitation has been shown to be more pH stable than silica [5]; titania-zirconia composites synthesized by the sol-gel method showed higher phosphopeptide enrichment efficiency than using single metal oxides [6]. Titania-coated separation materials have been widely used in various separation applications, particularly in high performance liquid chromatography (HPLC) [7][8][9][10], capillary electrophoresis (CE) [11][12][13][14], and solid-phase microextraction (SPME) [15][16][17][18]. Based on the Lewis acid-base interaction between titania and phosphate groups, the use of titania-coated materials has been applied in proteomics and phosphoproteomics [19][20][21][22].…”

Immobilized polymeric stationary phases using metalized silica supports

“…Besides PMOS, PBD was also deposited on 5 lm titanized silica particles and immobilized by microwave radiation [19]. The immobilization procedure was carried out in two distinct ways.…”

“…This type of phase usually involves an immobilization step, which supplies a better distribution of polymer onto the chromatographic support and higher stability of the stationary phase due to a better covering of the silanol groups [13]. Immobilization procedures that have been evaluated and that result in stationary phases with similar chromatographic performances to the bonded phases include gamma radiation [12,[16][17][18], microwave radiation [19], and thermal treatment [12,[20][21][22] in the presence or the absence of radical initiators. However, the main disadvantage of immobilized polymers on silica particles is the inhomogeneity of the polymeric covering of the support [23].…”

“…Recently, LabCrom has produced some stationary phases with polymers (polybutadiene and polysiloxanes) immobilized onto silica particles coated with more stable oxide layers (zirconia or titania) [17,19,[33][34][35][36], the socalled metalized silica supports. These supports incorporate the ideal chromatographic characteristics of silica to the stability of the alternative oxides [37,38].…”

Grafting of titanium dioxide microspheres with a temperature‐responsive polymer via surface‐initiated atom transfer radical polymerization without the use of silane coupling agents

“…Materials based on various structural modifications of titanium dioxide have numerous applications, among which are photocatalysis, 1 -3 photovoltaics, 4,5 photonics, 6,7 lithium-ion batteries, 8 -10 as well as sorbents for radionuclides 11 -13 and stationary phases for HPLC. 14 -16 Many applications require the use of spherical particles. For instance, ball-shaped particles improve flow properties and this is ideal for adsorption or chromatography packing materials.…”