Characterization of a water-soluble polysaccharide from Boletus edulis and its antitumor and immunomodulatory activities on renal cancer in mice

Purification, characterization and immunomodulatory activity of a polysaccharide from Celosia cristata

“…This implies that galactose and mannose present in CP1-1 might contribute to its immunomodulatory activity. CP1-1 presented immunomodulatory may be also due to its main composition of 1,6-linked galp (5.6%) and 1,6-linked glcp (3.8%) linkage characteristics that contribute to the immunomodulatory activity in polysaccharides from Boletus edulis (Wang, Sun, Wu, Yang, & Tan, 2014). In this study, we successfully isolated and characterized a bioactive polysaccharide CP1-1 from C. cristata.…”

Structural characterization, sulfation and antitumor activity of a polysaccharide fraction from Cyclina sinensis

“…In the present study, the improvement of antiproliferative activity might be due to the decreased molecular weight of CSPS-1 after sulfation. Many studies have suggested that the polysaccharides exert their antitumor effects by inducing apoptosis or activating immune responses in the host (Wang, Sun, Wu, Yang, & Tan, 2014). However, the mechanisms of antitumor action of the sulfated CSPS remain unclear.…”

Carbohydrates Against Cancer

“…Grifola frondosa, Hericium erinaceum, Lentinus edodes, Penicillium jiangxiense, Pleurotus abalonus, Pleurotus ostreatus, Polyporus sp., Poria cocos, Inonotus sp., Schizophyllum communes, Trametes hirsuta, Trametes versicolor, Tremella sp. and Tricholoma aggregatum are among the recent studied mushrooms with astonishing anticancer effect, which is assigned to their polysaccharides (Chang 2007;Zong et al 2012;Shenbhagaraman et al 2014;Wang et al 2014).…”