Characterization of an oxidized alginate-gelatin hydrogel incorporating a COS-salicylic acid conjugate for wound healing

Horseradish peroxidase catalyzed grafting of chitosan oligosaccharide with different flavonols: structures, antioxidant activity and edible coating application

“…thymol, dithiocarbamate, cinnamyl alcohol, geraniol, kojic acid, urea and polyphenolic compounds) to further improve the bioactivities of COS. [6][7][8][9][10][11][12] Recently, some researchers have demonstrated that the bioactivities of COS can be effectively elevated by grafting with polyphenolic compounds. 9,13 The prepared COS-polyphenol conjugates have potent antioxidant, [14][15][16][17] antiinflammatory, 18 anti-allergic, 19 ⊎-secretase inhibitory 20 and antibacterial activities. 21 Meanwhile, these COS-polyphenol conjugates have wide applications in wound healing, 16 biomedical dressing 21 and drug delivering.…”

“…9,13 The prepared COS-polyphenol conjugates have potent antioxidant, [14][15][16][17] antiinflammatory, 18 anti-allergic, 19 ⊎-secretase inhibitory 20 and antibacterial activities. 21 Meanwhile, these COS-polyphenol conjugates have wide applications in wound healing, 16 biomedical dressing 21 and drug delivering. 22 Nowadays, chemical methods including carbodiimide coupling method 14,15,18,22 and free radical grafting method 16,17,21 are normally used in the preparation of COS-polyphenol conjugates.…”

“…21 Meanwhile, these COS-polyphenol conjugates have wide applications in wound healing, 16 biomedical dressing 21 and drug delivering. 22 Nowadays, chemical methods including carbodiimide coupling method 14,15,18,22 and free radical grafting method 16,17,21 are normally used in the preparation of COS-polyphenol conjugates. However, the chemical method usually requires a high quantity of chemical reagents that are toxic and environmentally disadvantageous.…”

“…The prepared COS–polyphenol conjugates have potent antioxidant, 14‐17 anti‐inflammatory, 18 anti‐allergic, 19 β‐secretase inhibitory 20 and antibacterial activities 21 . Meanwhile, these COS–polyphenol conjugates have wide applications in wound healing, 16 biomedical dressing 21 and drug delivering 22 …”

Immunoregulation and anti-metalloproteinase bioactive injectable polysalicylate matrixgel for efficiently treating osteoarthritis

“…At present, clinical treatments for early osteoarthritis are based on oral non-steroidal anti-inflammatory drugs [ 13 ]. One constituent of these drugs is salicylic acid, which has good anti-inflammatory, antioxidant, and analgesic effects [ [14] , [15] , [16] ]. Salicylic acid has also been used in the treatment of human skin diseases and arthritis owing to its good biocompatibility and biological activity [ [17] , [18] , [19] ].…”