2023
DOI: 10.3390/diagnostics13030426
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Characterization of Anesthesia in Rats from EEG in Terms of Long-Range Correlations

Abstract: Long-range correlations are often used as diagnostic markers in physiological research. Due to the limitations of conventional techniques, their characterizations are typically carried out with alternative approaches, such as the detrended fluctuation analysis (DFA). In our previous works, we found EEG-related markers of the blood–brain barrier (BBB), which limits the penetration of major drugs into the brain. However, anesthetics can penetrate the BBB, affecting its function in a dose-related manner. Here, we… Show more

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Cited by 3 publications
(4 citation statements)
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“…Our work is the first to provide information on modulation of the majority of 35 APW‐Ps by ISO and ZO/XY anesthesia. The comparison of control APW‐P values acquired under ISO and ZO/XY anesthesia (Figure 1; Table 1) confirms published data that both types of anesthesia influence the cardiovascular system differently 28–31 . In the case of volatile anesthetic ISO, our control APW‐Ps for systolic BP, diastolic BP, and heart rate were similar, but the pulse BP was lower as that reported by Albrecht et al 29 (Table 1).…”
Section: Discussionsupporting
confidence: 86%
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“…Our work is the first to provide information on modulation of the majority of 35 APW‐Ps by ISO and ZO/XY anesthesia. The comparison of control APW‐P values acquired under ISO and ZO/XY anesthesia (Figure 1; Table 1) confirms published data that both types of anesthesia influence the cardiovascular system differently 28–31 . In the case of volatile anesthetic ISO, our control APW‐Ps for systolic BP, diastolic BP, and heart rate were similar, but the pulse BP was lower as that reported by Albrecht et al 29 (Table 1).…”
Section: Discussionsupporting
confidence: 86%
“…These results support the hypotheses that it is possible to characterize the cardiovascular system in many pathophysiological conditions or actions of bioactive substances just from the detailed shape of APWs 5,6,10,11,39–42 . Unfortunately, it is not fully known which signaling pathway(s) are influenced by these anesthetics 28–31,33 . If it is known, we might speculate what changes in APW‐Ps reflect particular pathway(s).…”
Section: Discussionsupporting
confidence: 81%
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