Jasminum sambac (Oleaceae) is a multi-functional plant that is used as decoration, traditional medicine, and a source of essential oil. This study aims to explain the botany, bioactivity and essential oil of J. sambac. The research method with online library research is mainly sourced from Google Scholar using the keywords J. sambac, uses of J. sambac and J. sambac essential oil. The essential oil of J. sambac is one of the most expensive oils used in the cosmetic, pharmaceutical, perfumery and aromatherapy industries. In traditional medicine J. sambac is used to treat dysmenorrhea, menorrhea, ringworm, leprosy, skin diseases, analgesic, antidepressant, anti-inflammatory, antiseptic, aphrodisiac, sedative, expectorant, fever, pain and inflammation and cancer. The bioactivity of J. sambac is to suppress lactation, analgesic, anti-microbial, antioxidant, anti-cancer, anti-hypertensive, treat wounds, treat ulcers. The distinctive aroma of J. sambac flowers is related to the content of essential oils, namely linalool, α- farnesene, d-nerolidol, geraniol, α-cadinol, benzyl alcohol, benzaldehyde, benzyl acetate, benzyl benzoate, 3-hexen-1-ol benzoate, and (Z) -3-hexen-1-ol acetate. The bioactivity of J. sambac as an anti-microbial can be developed as a natural food preservative and also to keep the body fresh.