Characterization of bis‐Schiff bases synthesized using ZnFe₂O₄ nanoparticles as catalyst, and examination of their antibacterial and in vitro cytotoxic properties

Abstract

In this study, ZnFe2O4 nanoparticles (NPs) were prepared by a hydro/solvothermal method, and their structures were characterized by infrared, scanning electron microscopy, energy‐dispersive X‐ray spectroscopy and X‐ray diffraction analyses. These ZnFe2O4 NPs were used in the synthesis of new bis‐Schiff bases by condensation of hydroxyl‐substituted aldehydes with various aromatic diamines in aqueous media. The antimicrobial activities of the synthesized bis‐Schiff bases were tested against gram‐negative as well as gram‐positive bacteria. The MTT method was used to assess the anticancer activity of the bis‐Schiff bases towards human lung and breast cancer cell lines. The results indicated that these compounds could be considered as new anti‐tumor candidates.

Crystal structure and molecular docking study of diethyl 2,2′-({[(1E,1′E)-(hydrazine-1,2-diylidene)bis(methanylylidene)]bis(4,1-phenylene)}bis(oxy))diacetate

“…Furthermore, these derivatives represent an important class of organic compounds, especially in the medicinal and pharmaceutical fields (Murtaza et al, 2014). It is well known from the literature that Schiff bases display excellent biological properties, such as antioxidant and analgesic (Karrouchi et al, 2016), antibacterial and cytotoxic (Maaref et al, 2020), antidiabetic (Karrouchi et al, 2022) and anti-inflammatory activities (Rana et al, 2012). These derivatives are also used as corrosion inhibitors, which relies on their ability to spontaneously form a monolayer on the surface being protected (El Arrouji et al, 2020).…”

NiO Nanoparticles: A Highly Efficient Catalyst For One-Pot Three-Component Synthesis of Pyrano[2, 3-d]Pyrimidine Derivatives in Green Media

“…Condensation reaction is among those chemical activities for which devising a new environmentally friendly catalyst could potentially provide an approach for dealing with the aforementioned challenges. Upon our previous study on synthesis of organic compounds by nanoparticles [26][27][28][29], the scope of the present work was to achieve the multi-component pyrano [2, 3-d] pyrimidines by using NiO nano powders as a green, environmentally friendly catalyst (Scheme 1).…”

Synthesis and characterization of LaMnO3 nanocrystals and graphene oxide: fabrication of graphene oxide–LaMnO3 sensor for simultaneous electrochemical determination of hydroquinone and catechol

“…Electrochemical methods have some attractive advantages such as simple and fast response, low maintenance cost, excellent selectivity and high sensitivity. However, a serious obstacle is that the oxidation peak potentials of the isomers are too close at a bare electrode which causes overlapping of voltammetric responses, making their discrimination very difficult [13][14][15][16][17]. A chemically modified electrode is a superior approach to solve the peak separation problem by applying a modifier [18][19][20][21][22][23][24].…”