During the design and development of a reliable transceiver, its performance and robustness are evaluated using channel models that simulate the propagation channel characteristics in a real-world environment. In the case of wide-area communication systems in rural areas such as those based on TV white spaces, long delay multipath fading is one of the dominant factors impairing communication quality, and it is important to apply realistic multipath fading channel models in various application scenarios. Therefore, it is necessary to develop channel measurement and modeling systems that adaptively obtain channel factors and reflect multipath propagation characteristics in various wide-area communication environments. In this study, we developed a flexible channel measurement and modeling prototype applicable to mobile IEEE 802.22-based wide-area communication systems, which can be simply implemented by using programmable hardware and software. The prototype includes a new channel modeling framework that applies an improved double exponential slope model to extract the essential factors of multipath propagation characteristics. To validate the developed prototype, a fading emulator is applied to it to measure the raw data used for modeling. As a result, the multipath fading characteristics measured with the prototype were successfully modeled and reproduced by the proposed channel modeling framework with a high fitness of root mean square delay spread distribution. The derived bit error rate characteristics agreed better with the simulation results compared to the conventional channel model.