The general position number $$\mathrm{gp}(G)$$
gp
(
G
)
of a connected graph G is the cardinality of a largest set S of vertices such that no three distinct vertices from S lie on a common geodesic; such sets are refereed to as gp-sets of G. The general position number of cylinders $$P_r\,\square \,C_s$$
P
r
□
C
s
is deduced. It is proved that $$\mathrm{gp}(C_r\,\square \,C_s)\in \{6,7\}$$
gp
(
C
r
□
C
s
)
∈
{
6
,
7
}
whenever $$r\ge s \ge 3$$
r
≥
s
≥
3
, $$s\ne 4$$
s
≠
4
, and $$r\ge 6$$
r
≥
6
. A probabilistic lower bound on the general position number of Cartesian graph powers is achieved. Along the way a formula for the number of gp-sets in $$P_r\,\square \,P_s$$
P
r
□
P
s
, where $$r,s\ge 2$$
r
,
s
≥
2
, is also determined.