Characterization of coronavirus disease 2019 (COVID-19) in children and adolescents in Latin American and the Caribbean countries: A descriptive study

Atamari‐Anahui, Noé; Cruz-Nina, Nelson Deyvis; Condori-Huaraka, Mirian; Núñez-Paucar, Héctor; Rondón-Abuhadba, Evelina Andrea; Ordoñez-Linares, Marco Edmundo; Pereira-Victorio, César Johan

doi:10.5867/medwave.2020.08.8025

Cited by 7 publications

(5 citation statements)

References 27 publications

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“…On February 29 th the rst case was reported in Ecuador, in August approximately 94,000 cases had been con rmed, with an accumulated incidence of 193,57 per 100000 habitants and 8.31% of lethality placing it as one of the countries with the highest mortality rate [4]. During this period 10000 thousand deceases more were registered in 2020 compared to 2019 in the same period time probably due to the collapse of health care system.…”

Section: Introductionmentioning

confidence: 95%

Mortality and Risk Factors in Patients With COVID-19 in Ecuador: A Cross-Sectional Analytic Study

Quizhpe

Montalvo²,

Páez³

et al. 2021

Preprint

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Background: In Ecuador, a high mortality was observed during the maximum peak of COVID-19 cases in spring/summer 2020. Thus, 10000 thousand more deaths were registered in 2020 compared to 2019 in the same period time. A few researchers in Latin America have identified clinical conditions that could be associated with severity and mortality of this disease. The aim of this study was to describe main clinical characteristics and risk factors in patients with COVID-19 in the Ecuadorian context. Methods: A cross sectional analytic study was conducted from March to July 2020. Adult patients with COVID-19 confirmed by PCR test and admitted in emergency service was included in this study. Descriptive statistical measures were computed, and Chi-squared and logistic regression were performed to analyze associations between categorical variables. Results: The main results of 157 patients, showed that had a high prevalence of comorbidities (45%), and the case-fatality rate in this group was around 37%. Hypertension (17.83%) and diabetes (14.65%) were the most prevalent chronic diseases with a significant difference between sex groups (p value 0.00). Risk factor such as age more than 65 years, presence of comorbidities such as non-communicable diseases, and abnormalities in blood markers like urea, AST, lactate, leucocytes, PO2 and D-dimer increased risk to die in this population. Conclusions: The elevated prevalence of non-communicable diseases (hypertension and diabetes) contributed to a high mortality in adult patients with COVID-19. Huge challenges must face health care systems in the Latin America countries due to the high prevalence of these diseases.

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Section: Introductionmentioning

confidence: 95%

Mortality and Risk Factors in Patients With COVID-19 in Ecuador: A Cross-Sectional Analytic Study

Quizhpe

Montalvo²,

Páez³

et al. 2021

Preprint

View full text Add to dashboard Cite

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“…The overall case fatality rate in Latin America has ranged from 0.8% in Cuba to 6.2% in Peru among Latin American countries with C 300,000 cumulative cases [13]. Additionally, although children and adolescents comprise a low percentage of COVID-19 cases in Latin America [14] (e.g., 12.5% in Chile through October 2021 [15]), COVID-19-associated hospitalizations and deaths in this population have been reported [14,16]. Deaths among children and adolescents (aged 0-19 years) ranged from 0% of the total number of COVID-19-associated deaths in Argentina, Chile, Costa Rica, Cuba, and Honduras to 9.1% in Haitı ´ [14].…”

Section: Regional Epidemiology Of Covid-19mentioning

confidence: 99%

COVID-19 in Latin America: A Snapshot in Time and the Road Ahead

LaRotta¹,

Escobar²,

Ávila-Agüero

et al. 2023

Infect Dis Ther

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Since its initial detection in Brazil in February 2020, SARS-CoV-2 and the associated COVID-19 pandemic have continued to devastate Latin America. Specific comorbidities, as well as sociodemographic and lifestyle factors that may be more prevalent in underserved areas, have been identified as risk factors for COVID-19 infection or associated adverse outcomes. Dynamics of infections and deaths in Latin America have varied by country and temporally, as has SARS-CoV-2 variant prevalence; however, more recently, the Delta and subsequent Omicron variants have become ubiquitous. Successful pandemic responses have involved robust infection mitigation measures, testing, and smart deployment of healthcare resourcing. While in some Latin American countries up to 90% of the population is fully vaccinated (i.e., 2 doses) against COVID-19, other countries have failed to reach the World Health Organization’s 70% target. Continued focus on comprehensive surveillance, strategies to maximize vaccine availability and uptake, and mitigation of collateral damage on other aspects of public health and social services are critical for managing the COVID-19 pandemic. This review summarizes the COVID-19 experience in Latin America, including epidemiology and vaccination. Key learnings and future considerations for the ongoing pandemic response are also discussed.

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“…These cases might have had some underlying comorbidity. For children, mortality is infrequent, and those admitted to intensive care units usually have a chronic or preexisting condition [27,34].…”

Section: Fatality Of Casesmentioning

confidence: 99%

Epidemiology of SARS-CoV-2 Infection in Mexico and Latin America

Padilla-Raygoza¹,

Flores-Vargas²,

Gallardo-Luna³

et al. 2023

Epidemiological and Clinico-Pathological Factors of COVID-19 in Children

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This chapter presents some insights into COVID-19 in children. We begin by summarizing the fundamental aspects of SARS-CoV-2 and COVID-19. We also cover issues about the severity of the disease and fatality and factors associated with the outcome of pediatric patients with COVID-19. Most evidence treated in this chapter comes from reports in Mexico, but a general landscape in Latin America is pictured. COVID-19 does not seem to be so severe among children. It is worth noting that those at higher risk are the children between 0 and 2 years who develop pneumonia. In this chapter, we did not discuss extensively the Multisystem Inflammatory Syndrome nor the social impact that the COVID-19 pandemic has had on children. Many studies used for this chapter relied on open data sources resulting from a surveillance system designed for the general population. Therefore, specific variables for children were not analyzed.

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Characterization of coronavirus disease 2019 (COVID-19) in children and adolescents in Latin American and the Caribbean countries: A descriptive study

Cited by 7 publications

References 27 publications

Mortality and Risk Factors in Patients With COVID-19 in Ecuador: A Cross-Sectional Analytic Study

Mortality and Risk Factors in Patients With COVID-19 in Ecuador: A Cross-Sectional Analytic Study

COVID-19 in Latin America: A Snapshot in Time and the Road Ahead

Epidemiology of SARS-CoV-2 Infection in Mexico and Latin America

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