Characterization of extraintestinal pathogenic Escherichia coli isolated from captive wild felids with bacteremia

Abstract

Diseases caused by extraintestinal pathogenic Escherichia coli (ExPEC) in wild felids are rarely reported. Although urinary tract infections are infrequently reported in domestic cats, such infections when present are commonly caused by ExPEC. The present work characterized ExPEC strains isolated from 2 adult felines, a snow leopard (Panthera uncia) and a black leopard (Panthera pardus melas), that died from secondary bacteremia associated with urinary tract infections. Isolates from both animals were classified into the B2 phylogenetic group and expressed virulence genotypes that allowed them to cause severe disease. In addition, strains from the black leopard showed multidrug resistance.

Free-Ranging Frigates (Fregata magnificens) of the Southeast Coast of Brazil Harbor Extraintestinal Pathogenic Escherichia coli Resistant to Antimicrobials

“…ExPEC, including specific pandemic lineages, are responsible for a significant incidence of disease processes in humans and domestic animals and have been linked to disease in wild animals kept in captivity [ 31 ], but ExPEC strains are rarely isolated from free-ranging wildlife [ 9 , 11 ]. Considering that the highest human population density in Brazil is concentrated close to the coastline ( http://censo2010.ibge.gov.br/apps/atlas/ ), the results of the present work might reflect the wide human action that contributes to the spread of potential pathogens to wildlife, and some of the findings discussed above may support this hypothesis.…”

Nasal, oral and rectal microbiota of Black lion tamarins (Leontopithecus chrysopygus)

“…Escherichia coli is known to be one of the most abundant saprophytic bacteria in the gastrointestinal tract of warm-blooded animals. However, pathogenic strains are important cause of diarrhoea and can also cause other pathologic conditions, including septicaemias, meningitis, urinary infections, abscesses and celulitis ( McClure et al , 1986 , Carvalho et al , 2003 , Blanco et al , 2004 , Carvalho et al , 2012 ). Indeed, E. coli seems to be a potential pathogen for callithrichids ( Mansfield et al , 2001 ).…”

Molecular characterization and Antibiotic resistance profiles of Escherichia coli extended-spectrum β-lactamases producer strains isolated from urine samples in Benin

“…E. coli, part of the human commensal Flore, is known to be the first bacteria to colonize humans gut. Indeed, E. coli belonging to the family of Enterobacteriaceae is an important opportunist human pathogen associated with infections such as urinary tract, surgical site, skin, soft tissues, bacteremia, and pneumonia infections (Pitout, 2012;Carvalho et al, 2012). Among those infections, urinary tract infections are considered as a public health problem (Fatna et al, 2009) because the urine of healthy person must be exempt of any microorganism (Foxman, 2002).…”