Characterization of forced degradation products of Netarsudil: Optimization and validation of stability-indicating RP-HPLC method for simultaneous quantification of process related impurities of Netarsudil
Bodasingi Sai Kumar,
Jammu Harish,
Bhagya Kumar Tatavarti
et al.
Abstract:Objectives
The aim of this study is to examine resolution, identification, and characterization of forced degradation products of netarsudil by liquid chromatography-tandem mass spectrometry by validating a simple and sensitive high-performance liquid chromatography method for the resolution, identification, and quantification of two process-related impurities in netarsudil.
Materials and Methods
Chromatographic separation was accomplished on a ZORBAX Eclipse XDB C18 (2… Show more
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