Climate change (CC) scenario is already acknowledged as one of those environmental challenges that threaten every facet of life including mango farming. This study was designed to investigate into mango farmers’ perception of the impacts of climate change (CC) on mango farming. A structured questionnaire was administered among 480 mango farmers across six of the states where mango farming is carried out in Nigeria. Both descriptive and inferential statistical methods were applied in the analysis of the data. From the 418 completed and returned questionnaires analysed, it was found that the male gender dominated the respondents in the survey with a proportion of 68% while 61% use pesticides to control pests and 35% own between 1 and 3 acres of mango farmland. The data were subjected to KMO and Bartlett’s tests, the results of which showed that the data are factorable with p≤0.05. Factor analysis (FA) extracted six (6) out of the fourteen (14) variables analysed which were significant to explain the perceptions of the farmers on the impact of CC on mango farming, namely: (i) change in the volume of mango production; (ii) effect of high temperature; (iii) prolonged dry season; (iv) rainfall pattern; (v) incidence of flooding; and (vi) poor performance of mango seedlings. Further analysis showed the prominence of issues relating to climate change. The implication of these results is that mango farming is also being threatened by CC. Hence, it calls for urgent mitigation actions to salvage this subsector. Farmers need to be adequately supported by stakeholders in their efforts to adapt to the ravaging effects of CC on mango farming through relevant policies and programmes. The work also recommended further investigation on the efficacy of the adaptive methods on mango yields.