Characterization of human MSC-like cells isolated from bone marrow, adipose tissue, skin and placenta.

The role of partial androgen deficiency in aging men in the development of benign prostatic hyperplasia and prostate cancer

“…Although people can keep their social function in their old age, the period of optimal functionality for human, as set by evolution, ends at the age of 35-40 years [3]. Once people reach 35-40 years of age, they have a decrease in their pool of pluripotent stem cells [4], show a violation of tissue renewal, a decrease in the number of cell-producers of testosterone (Leidig cells), and a reduction in testosterone circulating in the blood. This reduction is named partial androgen deficiency of aging men (PADAM) [5].…”