Characterization of hydrocarbon and fluorocarbon microdomains formed in aqueous solution of associative polymers: A molecular probe technique

Bioinspired Block Copolymers: Translating Structural Features from Proteins to Synthetic Polymers

“…Though polymer 1 was shown to produce micellar aggregates with lipophilic and fluorophilic compartments by selective solubilization experiments, [56] the respective compartments within the hydrophobic microdomains are too small to be detected by electron microscopy. Cryo-TEM of diluted aqueous solutions of these polymers shows thin, worm-like micelles with a diameter of 3.5 nm, but no smaller substructure within the aggregates can be seen ( Figure 6).…”

“…[34,35,38,39,43,44,[57][58][59][60][61][62][63] In contrast, the equally important aspect of dual, selective solubilization has been hardly addressed so far. [27,29,40,56,64] On the one hand, conclusive experiments of this type are not easy to perform. On the other hand, many of the hitherto studied multicompartment systems are characterized by lipophilic and/or fluorophilic nanodomains, which exhibit high glass transitions, as for instance in 2, or (semi-)crystallinity, as for instance in 3-5.…”

Multicompartment Micelles: Has the Long‐Standing Dream Become a Reality?

“…[6] Recent studies on hydrocarbon-and fluorocarbon-modified hydrophobic pyrene on related polysoap systems strengthen this picture. [13] These results emphasize that multicompartment micelles can be potentially used as nanocontainers for selective advanced drug-delivery applications.…”

“…According to our considerations above, B should be typically a hydrocarbon-dominated block whilst C should be a fluorocarbon-dominated block (or vice versa). The concept was realized most elegantly in the low-molecular-weight case using phospholipids bearing partially fluorinated fatty acids, namely 8,8,9,9,10,10,11,11,12,12,13,13,13-tridecafluorotridecanoic acid, leading to vesicles with an inner fluorocarbon zone and two outer hydrocarbon zones within the amphiphilic bilayer membrane. [10] Interestingly, in the polymer case, Nuyken and co-workers designed triblock copolymers with a different block sequence, namely of the type BAC, as a first type of a triblock copolymer with incompatible hydrophobic segments.…”

1-Acetylpyrene with dual functions as an environment-sensitive fluorophore and fluorescent photoremovable protecting group

“…1-Acylpyrenes are used as photoprobes 29,30 since their fluorescence properties are highly sensitive to medium polarity and the hydrogen bonding of the microenvironment. For example, 1-heptanoylpyrene 29 exhibits very low fluorescence in non-polar solvents like hexane or diethyl ether.…”