Characterization of initial clinical symptoms and risk factors for sinonasal adenocarcinomas: results of a case–control study

Mayr, Susanne; Hafizovic, Kamber; Waldfahrer, Frank; Iro, Heinrich; Kütting, Birgitta

doi:10.1007/s00420-009-0479-5

Cited by 28 publications

(20 citation statements)

References 49 publications

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“…Moreover, in the studies where nasosinusal cancers in timber workers had been reported, workers have always been exposed for a long period. Thus, in their studies, Mayr et al as well as Bimbi et al reported average exposure duration of 32.3 years in patients suffering from cancer associated with timber [13] [14]. The duration of average exposure of timber workers to sawdust in our study was 4.9 years, which does not give enough ground to associate the tumor observed to timber work.…”

Section: Discussioncontrasting

confidence: 66%

ENT Pathologies Screening in Woodworkers in Parakou, Benin

Hounkpatin¹,

Gounongbé²,

Afouda³

et al. 2014

IJOHNS

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Wood dust may induce health risks on exposed timber or wood workers, one of which is ENT disorders. This article aimed to detect ENT pathologies found among woodworkers in Parakou. It was a cross-sectional descriptive study carried out from 1 st March to 31 st May, 2012 in Parakou, NorthBenin. It involved 703 carpenters and sawyers operating in timber workshops in Parakou, regardless of age and sex. The mean age of the wood-workers was 26.14 ± 7.77 years. Their seniority in the timber profession was on average 4.9 ± 2.64 years. All of them were males. It had been noticed that 81.6% of them did not comply with any safety measure for their protection. ENT pathology had been diagnosed in 60.3% of the timber workers. Rhinitises came first and affected 43.1% of the workers, followed by pharyngitises (14.1%). The histological nature of the only case of tumor observed in Parakou could not have been specified, as the patient refused to undergo anatomopathological examination. Measures should be taken to get Parakou timber workers to protect themselves.

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Section: Discussioncontrasting

confidence: 66%

ENT Pathologies Screening in Woodworkers in Parakou, Benin

Hounkpatin¹,

Gounongbé²,

Afouda³

et al. 2014

IJOHNS

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“…Les signes rhinologiques sont au premier plan et le plus souvent les seuls. L'obstruction nasale unilatérale est de loin le signe le plus fréquent [29]. La rhinorrhée est purulente, séro-sanglante ou simplement séreuse.…”

Section: Signes Fonctionnelsunclassified

“…La rhinorrhée est purulente, séro-sanglante ou simplement séreuse. Les épistaxis sont volontiers minimes et répétées (notées dans 20 à 50 % des cas et ont l'avantage d'alarmer le patient et de le faire consulter) [29]. Enfin, l'anosmie est moins fréquente et associée à l'obstruction nasale à un stade avancé.…”

Section: Signes Fonctionnelsunclassified

“…D'ailleurs, Demers et al n'ont pas relevé d'association significative entre le carcinome épidermoïde et exposition aux poussières de bois [43]. Certaines études ont souligné que l'exposition aux particules de poussières de bois durs de type feuillus (chêne, hêtre) est associée avec la survenue d'adénocarcinome [1,22,29], alors que l'exposition aux particules de bois tendres de type résineux (sapin, pin) est associée au carcinome épidermoïde [1,22]. On a rapporté même des cas d'adénocarcinomes chez des patients exposés de façon non professionnelle au bois [44].…”

Section: Le Boisunclassified

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Cancers des cavités nasales et des sinus paranasaux : aspects clinicopathologiques, étiologiques et thérapeutiques

Rhif

2012

Bulletin du Cancer

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“…Carcinomas of the sinonasal tract are highly aggressive neoplasm arising from the nasal cavity and paranasal sinus. Although sinonasal carcinoma is rare, it must be suspected when facing with an ulcerated mucosa of this tract even in young patients [7]. Clinical presentation is usually that of epistaxis, nasal obstruction, nasal discharge with occasional bloody drainage, and serious otitis media which may be among the earliest symptoms.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Consideration for Sinonasal Wegener’s Granulomatosis Clinically Mistaken for Carcinoma

Rosa

Emmanuele

Tranchina

et al. 2013

Case Reports in Otolaryngology

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We report a case of Wegener's granulomatosis clinically mistaken for carcinoma in a 21-year-old girl presenting with an ulcerated mass of the nasopharynx associated with enlarged laterocervical nodes. The lesion was clinically suspected as malignant on the basis of clinical and radiological findings (namely, computed tomography scan and positron emission tomography). However, multiple biopsies were not conclusive for malignancy showing histological change suggestive of Wegener's granulomatosis. A serum determination of cANCA supported the diagnosis of Wegener's granulomatosis. Clinical findings and image studies suggested an erroneous diagnosis of malignancy whereas a definitive diagnosis of Wegener's granulomatosis was achieved only after repeated biopsies thus leading to a correct therapeutic approach. The Wegener granulomatosis must be added to the list of the differential diagnoses of the masses of the nasopharynx associated with or without enlarged laterocervical nodes.

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Characterization of initial clinical symptoms and risk factors for sinonasal adenocarcinomas: results of a case–control study

Abstract: Our investigation confirms the importance of regular screenings for persons exposed to wood dust even years after the end of occupational or private exposure. Banal clinical symptoms such as epistaxis and nasal obstruction might be predictive, requiring early and thorough investigation.

Cited by 28 publications

References 49 publications

ENT Pathologies Screening in Woodworkers in Parakou, Benin

ENT Pathologies Screening in Woodworkers in Parakou, Benin

Cancers des cavités nasales et des sinus paranasaux : aspects clinicopathologiques, étiologiques et thérapeutiques

Diagnostic Consideration for Sinonasal Wegener’s Granulomatosis Clinically Mistaken for Carcinoma

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