The SIR Iber shows the scientific activity of universities in Andorra, Spain, Portugal, and Latin American countries by positioning them based on measurement, research, innovation, and social impact factors (through a system of indicators). In this paper, the twelve (12) indicators of the research measurement factor of Latin American universities in the TOP 10 of the SIR Iber 2020 Ranking are analyzed and compared. Although the USP (Brazil) ranks first in Latin America, the University of Chile ranks first in the International Collaboration (IC), Normalized Impact (NI), Weighted Citation Normalized (WCN), High Quality Publications (Q1), Excellence (EXC), and Excellence with Leadership (EwL). A scatter diagram is presented between the Output (O) and Normalized Impact (NI) indicators, highlighting that there is no significant linear relationship between them.