Characterization of lncRNA functioning in ovine conceptuses and endometria during the peri-implantation period

Matsuno, Yuta; Kusama, Kaoru; Imakawa, Kazuhiko

doi:10.1016/j.bbrc.2022.01.064

Cited by 2 publications

(2 citation statements)

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“…Expression of lncRNA in female reproductive tracts, particularly when expressed in utero during peri-implantation periods, has been characterized in pigs (60)(61)(62)(63), goats (64), sheep (65), and mice (66). Quite recently, Matsuno et al (67) analyzed the lncRNA profiles present in utero on days 15, 17, 19 and 21 of pregnancy in sheep. Among 8,808 lncRNAs identified, 3,423 lncRNAs were novel.…”

Section: Emerging Role Of Lncrna In Conceptus Implantationmentioning

confidence: 99%

“…Among 8,808 lncRNAs identified, 3,423 lncRNAs were novel. Using gene ontology analysis, lncRNA target genes were enriched for cellular processes involved in the respiratory electron transport chain (RETC) (67). The results from these analyses suggest that in addition to secretomes, lncRNA is a potential new regulator in ovine conceptus development during peri-implantation periods.…”

Section: Emerging Role Of Lncrna In Conceptus Implantationmentioning

confidence: 99%

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New Roles for EVs, miRNA and lncRNA in Bovine Embryo Implantation

2022

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The sine qua non of new life is fertilization. However, approximately 50% of fertilized eggs/blastocysts in cattle and up to 75% of those from human assisted reproductive procedures fail during the first 3 to 4 weeks of pregnancy, including peri-implantation periods. In these periods, blastocyst hatching and implantation to the maternal endometrium proceeds, during which physiological events such as epithelial-mesenchymal transition (EMT) and trophoblast cell fusion occur. Quite recently, extracellular vesicles (EVs) with micro RNAs (miRNAs) and long non-coding RNAs (lncRNAs) have been found to play a pivotal role for the establishment of the proper uterine environment required for peri-implantation processes to proceed. New findings of EVs, miRNA, and lncRNAs will be described and discussed to elucidate their connections with conceptus implantation to the maternal endometrium.

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