Over the past decade, there has been an increasing number of case reports of bronchopulmonary infection due to Lophomonas spp. The Caribbean has not been included in any reports. We describe two cases of bronchopulmonary infection due to
Lophomonas
spp. We also describe successful treatment with metronidazole and an alternative, albendazole. We also briefly review the controversy of
Lophomonas
spp. as a true pathogen and the population groups affected.