Characterization of Magnetic Polymeric Microparticles

Abstract

Abstract:The separation process is very important in a variety of scientific fields, especially in biochemistry and biotechnology. The separation performance of a method can be determined by the separation time and the purity of the separated molecule, which is directly proportional with the ligand chosen for the target molecule. The separation time is actually a very important step for the cost and the time-dependent analysis, especially in medical applications. Magnetic separation is a very advantageous technique because it eliminates the time-consuming sample preparation and centrifugation steps. However, the magnetic performance of adsorbent may not be strong enough to respond the magnetic force applied externally. Therefore, in nanoparticle studies, magnetic performance of nanoparticles is highly important. In this study, the magnetic performance of polymeric microparticles synthesized using different magnetic cores (Fe2O3 & Fe3O4, Fe & Ni, Ni & Co, Fe & Ni & Co) with a solid support, HEMA (2-hydroxyethylmethacrylate), and a functional monomer, AdeM (adenine methacrylate), were compared. Some other properties such as size, zeta potential, surface morphology, etc. were also studied.

Nicotinamide-Modified poly(HEMA-GMA)-Nic Cryogels for Removal of Pesticides

“…As can be seen from Figure 3B, the synthesized cryogels have cavities that allow the analyte to diffuse readily. The presence of holes in the porous structure, having a water retention capacity of about ~800%, although having a surface area of ~8.5 m 2 /g less than microparticles or nanoparticles (28)(29)(30)(31)(32)39), provides the necessary retention time for the analyte to interact with ligand within polymeric structure. Ability to swallow high amount of analytes and the cavities connected with interconnected flow channels are the critical properties of cryogels providing them to be indispensable absorbents.…”

“…In particular, the micro-and macroporous structure of cryogels overcome the disadvantages in conventional techniques. The primary downside of cryogels over micro-and nano-adsorbents is that they seem to have a low surface area, but they also eliminate many problems coming from these adsorbents such as agglomeration, low yield, and the need for highperformance devices such as centrifuges (28)(29)(30)(31)(32). Polymeric cryogels have interconnected flowchannels providing the diffusion of the target molecule to the cavities of the cryogels, therefore, this provides a healthy interaction between the ligands on the surface of cryogels and the target molecules residing on the cavities for a while (33).…”