Characterization of Oral Veillonella Species in Dental Biofilms in Healthy and Stunted Groups of Children Aged 6–7 Years in East Nusa Tenggara

Abstract

Impaired development that causes stunting is one of the most common health problems in Indonesia. In particular, the highest number of cases of stunting in Indonesia was reported in the East Nusa Tenggara (NTT) province. Previous studies have shown a tendency for deteriorating oral hygiene in children with a poor nutritional status. In addition, a higher proportion of oral Veillonella has been reported in children with poor oral hygiene. However, the relationship between populations of oral Veillonella and stunting has not been studied before. Therefore, this study aimed to analyze the oral Veillonella profile in the dental biofilms of healthy and stunted children aged 6–7 years. The participants were 60 elementary school students in the Nangapanda District, Ende, NTT, Indonesia. In this study, real-time polymerase chain reaction was used to examine dental biofilm samples from the healthy (n = 31) and stunted (n = 29) groups. The results revealed that seven oral Veillonella species were found in all groups. However, the number of four oral Veillonella species significantly differed between the healthy and stunted groups: V. denticariosi, V. infantium, V. rogosae, and V. tobetsuensis. This is the first study to demonstrate a potential association between oral Veillonella species and stunting in children.

Oral microbial signatures associated with age and frailty in Canadian adults

“…With respect to frailty, Ogawa et al found signi cant differences in several genera between individuals living in nursing homes compared to independent living including Veillonella, Capnocytophaga, Fusobacteriuim, Leptotrichia, Streptococcus, and Selenomonas which is consistent with our ndings with at two or more DA tools (Table 2). Veillonella are anaerobic gram-negative bacteria that ferment organic acids, such as lactate 42 , and may be re ective of oral hygiene and number of teeth [43][44][45] and has been linked to increased cardiometabolic risk 46 .…”

“…Medications 617 [45] 339 [25] 418 [30] 216 [48] 105 [24] 125 [28] 401 [44] 234 [26] 276 [30] Frailty and age show divergence in alpha diversity patterns…”

Propolis Fluoride Inhibits Streptococcus mutans and Veillonella parvula Dual- species Biofilm Growth and alters Gene Expression

“…According to the optimum oral environment, genus Veillonella live in association with lactic acidproducing species, such as S. mutans, as early colonizer of dental bio lms, which causes the continuation of colonization by dental bio lm bacteria and decreases the pH of the oral environment to become acidic [2]. Oxidative response is necessary for prokaryotic organisms to survive.…”

“…A dental bio lm is a functional, multispecies, and complex bacterial community containing viable and nonviable bacteria and their metabolites encapsulated in a saliva-derived polymer matrix [1]. A mature dental bio lm with dysbiotic bacterial composition is known to be the cause of most oral diseases, including gingivitis, periodontitis, and dental caries [1,2]. Prevention of oral diseases is crucial and cheaper than curative oral and dental treatment, making it a sustainable target as an oral health intervention.…”