Characterization of particle morphology of biochanin A molecularly imprinted polymers and their properties as a potential sorbent for solid-phase extraction

Chrzanowska, Anna M.; Poliwoda, Anna; Wieczorek, Piotr

doi:10.1016/j.msec.2015.01.069

Cited by 30 publications

(12 citation statements)

References 30 publications

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“…In the FTIR spectrum of biochanin A, a strong, broad absorption band in the range of 3400-3200 cm −1 with maximum at 3261 cm −1 is assigned to valence vibrations of phenolic OH groups, ν(OH). The characteristic valence vibrations of the phenolic C-O bond, ν(C-O)Ar, gave astrong band in the range of 1260-1000 cm −1 , which is located at 1176 cm −1 in the spectrum of biochanin A [14,49,50]. In-plane deformation vibrations of hydroxyl groups, δ(OH), occur in the range of 1500-1300 cm −1 and give a low-intensity band with maximum at 1323 cm −1 in the spectrum of biochanin A.…”

Section: Number Of Experimentsmentioning

confidence: 99%

Modified Biochanin A Release from Dual pH- and Thermo-Responsive Copolymer Hydrogels

et al. 2021

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The temperature- and pH-responsive poly(N-isopropylacrylamide-co-acrylic acid), p(NIPAM-co-AA), copolymer was synthesized by free radical polymerization and examined as a carrier for modified release of biochanin A. Biochanin A is a biologically active methoxylated isoflavone which exhibits estrogenic and other pharmacological activities. Due to its poor aqueous solubility and extensive first-pass metabolism, biochanin A has low bioavailability. The aim of this work was to incorporate biochanin A into the synthesized p(NIPAM-co-AA) copolymer and to examine its release at the body temperature and pH values that correspond to pH values of vaginal and rectal cavities. The amount of released biochanin A was monitored by the ultra-visible spectroscopy (UV-Vis) method. The structure of synthesized p(NIPAM-co-AA) copolymer and copolymer with incorporated biochanin A were characterized by using Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) methods. The content of residual monomers in the synthesized copolymer was analyzed by using the high-pressure liquid chromatography (HPLC) method. The swelling behavior of p(NIPAM-co-AA) copolymer was monitored in relation to the temperature and pH values of the surrounding medium. For modelling the process of p(NIPAM-co-AA) copolymer swelling, the full three-level factorial design was applied.

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Section: Number Of Experimentsmentioning

confidence: 99%

Modified Biochanin A Release from Dual pH- and Thermo-Responsive Copolymer Hydrogels

et al. 2021

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“…The kinetic adsorption test was carried out by using EMIPs or ENIPs (20 mg) that were dispersed in the E1 aqueous solution (10 mL) and shaken at room temperature for different time (5,10,15,20,30,45,60,90, and 120 min), and then filtered. The supernatant was measured by HPLC and the adsorption capacity was calculated.…”

Section: Adsorption Testmentioning

confidence: 99%

“…In recent years, molecularly imprinted polymers (MIPs) have been widely used as SPE adsorbents for selective extraction of target molecules from environment or biological samples, because of specific selectivity, easy preparation, good chemical stability, and excellent recognition properties of MIPs . However, the conventional MIPs prepared by bulk polymerization or precipitation polymerization show some disadvantages such as low absorption capacity, poor site accessibility and slow mass transfer, which could be attributed to the highly cross‐linked nature of MIPs that templates were embedded deeply in the polymer matrices and caused the difficulty of the removal of the templates . Because surface imprinted polymers exhibit high binding capacities, fast mass transfer, and rapid binding kinetics due to the easy accessibility to recognition sites, surface imprinted technique is becoming one of the most effective ways to prepare the MIPs .…”

Section: Introductionmentioning

confidence: 99%

Facile preparation of polydopamine‐coated imprinted polymers on the surface of SiO₂ for estrone capture in milk samples

Zheng

Zhang

Luo

et al. 2016

J of Separation Science

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Estrone molecularly imprinted polymers were synthesized through the self-polymerization of dopamine on the surface of silica gels, which had the characteristics of mild polymerization conditions, simple reaction procedure and good specific recognition ability for estrone. The estrone molecularly imprinted polymers were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis, elemental analysis and nitrogen adsorption-desorption tests. The characterization confirmed that the imprinted polymers were successfully grafted on the surface of silica gels. Through investigating the adsorption performance, the prepared estrone molecularly imprinted polymers exhibited high adsorption capacity, fast mass transfer, as well as excellent selectivity toward estrone. The estrone molecularly imprinted polymers as the solid-phase extraction adsorbent coupled with high-performance liquid chromatography was developed to determine estrone from the milk samples. The developed estrone molecularly imprinted polymer solid-phase extraction with high-performance liquid chromatography method exhibited satisfactory specificity, precision, accuracy and good linearity relationship in the range of 0.2-20 μg/mL. The developed method is simple, fast, effective and high specificity method and it provides a new method to detect the residues of estrone in animal foods.

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“…[12] The performance of the composite latex particles is directly affected by their morphology and due to its practical importance, particle morphology has received a considerable attention in the literature. [13][14][15][16][17][18][19][20][21][22][23][24][25][26] Several authors reported theoretical approaches aimed at predicting the particle morphology, but most of the methods are based on two limiting assumptions: either the polymer chains do not move from the point that they are formed [25,[27][28][29][30][31] or the equilibrium morphology is attained instantaneously. [11,[32][33][34][35][36][37][38][39][40] There are only few works in the literature that take into account all relevant kinetic and thermodynamic effects.…”

Section: Introductionmentioning

confidence: 99%

A new approach for mathematical modeling of the dynamic development of particle morphology

Hamzehlou

Leiza

Asúa

2016

Chemical Engineering Journal

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Please cite this article as: S. Hamzehlou, J.R. Leiza, J.M. Asua, A new approach for mathematical modelling of the dynamic development of particle morphology, Chemical Engineering Journal (2016), doi: http://dx. AbstractA new model for the dynamic evolution of the morphology of polymer-polymer latex particles has been developed. This model overcomes the limitations of the existing methodologies that were only able to provide the morphology of a single particle, which is only a restricted view of the real system that contains a distribution of particle morphologies. Taking into account the relevant kinetic and thermodynamic effects, the new model calculates the distribution of morphologies for the whole population of polymer particles with less computational effort than that needed by the previous models to calculate the morphology of a single particle. The model was validated by fitting the evolution of particle morphology of composite particles during polymerization of methyl methacrylate on a polystyrene seed. Furthermore, the ability of the model to predict the evolution of the particle morphology for different cases was explored.

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Characterization of particle morphology of biochanin A molecularly imprinted polymers and their properties as a potential sorbent for solid-phase extraction

Cited by 30 publications

References 30 publications

Modified Biochanin A Release from Dual pH- and Thermo-Responsive Copolymer Hydrogels

Modified Biochanin A Release from Dual pH- and Thermo-Responsive Copolymer Hydrogels

Facile preparation of polydopamine‐coated imprinted polymers on the surface of SiO₂ for estrone capture in milk samples

A new approach for mathematical modeling of the dynamic development of particle morphology

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Characterization of particle morphology of biochanin A molecularly imprinted polymers and their properties as a potential sorbent for solid-phase extraction

Cited by 30 publications

References 30 publications

Modified Biochanin A Release from Dual pH- and Thermo-Responsive Copolymer Hydrogels

Modified Biochanin A Release from Dual pH- and Thermo-Responsive Copolymer Hydrogels

Facile preparation of polydopamine‐coated imprinted polymers on the surface of SiO2 for estrone capture in milk samples

A new approach for mathematical modeling of the dynamic development of particle morphology

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Product

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Facile preparation of polydopamine‐coated imprinted polymers on the surface of SiO₂ for estrone capture in milk samples