Characterization of patients with psoriatic arthritis in dermatologic and rheumatologic care: analysis of two registries

Abstract

SummaryBackground and objectivePsoriatic arthritis (PsA) is a chronic systemic inflammatory disease affecting the musculoskeletal system, skin and nails. The aim is to characterize sociodemographic and clinical patient profiles documented in dermatologic and rheumatologic care.Patients and MethodsData of 704 patients with PsA from the dermatological Psoriasis Registry PsoBest (PB) and 1066 patients from the rheumatological disease registry RABBIT‐SpA (RS) were analyzed. Comparable anamnestic and clinical variables were identified and descriptively analyzed.ResultsThe mean age was 51.7 years in PB and 51.9 in RS. Disease duration of psoriasis was longer, mean cutaneous severity was higher in PB. However, more patients in RS vs. PB had tender joints and swollen joints. Mean Dermatology Life Quality Index was higher in PB and mean Health Assessment Questionnaire in RS. Patient reported global disease activity and pain were lower in PB. IL‐23 inhibitors were used more frequently in PB, and TNF inhibitors in RS.ConclusionsClinical specialization was associated with different clinical and treatment patterns of PsA. This may indicate a selection by dominant manifestation of psoriatic disease and potentially by effects of health care access. Psoriatic arthritis should be treated in a multidisciplinary approach considering all facets of this complex disease.

Nail Psoriasis: Clinical Features and Severity Assessment

“…The initiation of registry studies has facilitated research on clinical presentations at relatively low prevalence rates. Reports from Germany’s psoriasis registry, PsoBEST, and the rheumatoid arthritis registry (RABBIT) indicate that nail psoriasis was observed in 58% and 41% of patients with psoriatic arthritis, respectively 10 . The variations in nail psoriasis prevalence between these two registries may be attributed to the differences in the specialties of the physicians who identified and recorded nail psoriasis symptoms.…”

Warum wir Register(daten) brauchen

“…Augustin et al. haben daher die beiden Psoriasis‐Arthritis‐Kohorten der Register PsoBest und RABBIT‐SpA charakterisiert und miteinander verglichen 5 …”