Characterization of phenolic pellets for ESR dosimetry in photon beam radiotherapy

Abstract

» Download abstractWe report a study of the dosimetric features of phenolic compounds for applications in radiation therapy dosimetry of clinical photon beams by using ESR spectroscopy. After the optimization of the ESR readout parameters, basic dosimetric properties (such as intra-batch reproducibility, dose-response, sensitivity, linearity, dose rate dependence, tissueequivalence and signal stability) of laboratory-made phenolic dosimeters in form of pellets were investigated. Furthermore, these dosimeters were tested for measuring the depth dose profile of a 6 MV clinical photon beam. The results reported show that these dosimeters are promising materials for ESR dosimetric applications in radiation therapy.

ESR dosimeter material properties of phenols compound exposed to radiotherapeutic electron beams

“…It is possible to assess that the phenolic dosimeters have similar ESR response (within 3%) for the various energies considered. A comparison of these values with those obtained for irradiations with LINAC photons shows that the response to electrons is also similar (within experimental uncertainties) to that observed for photon exposure [67].…”

“…In particular using 6 MV LINAC photon beams as a reference clinical beam [67] and various electron beams with different energies namely 7, 10 and 14 MeV.…”

“…Recently, the ESR features of some IRGANOX Ò 1076 phenols compounds (IUPAC name octadecyl 3-(3,5-ditert-butyl-4-hydroxy phenyl) propanoate) have been analyzed and promising properties have been found such as high efficiency of radiation-matter energy transfer and radical stability at room temperature for irradiation with photons and neutrons in both pellet and film shape [64][65][66][67].…”

Temperature behavior of radiochromic poly(vinyl-alcohol)-glutaraldehyde Fricke gel dosimeters in practice

“…Over the years, several different systems able to measure the quantity and quality of ionizing radiation in radiation therapy (RT) have been developed [1][2][3]. These include, for instance, ionization chambers, radiographic and radiochromic films, semiconductor detectors, thermoluminescent and optically stimulated luminescent detectors, scintillation dosimeters and electron spin resonance dosimeters [4][5][6][7][8][9]. Currently, there is a wide choice of dosimeters that can allow to characterize radiation beams used in RT practices [10,11].…”

Alanine films for EPR dosimetry of low-energy (1–30 keV) X-ray photons

“…Nowadays, electron paramagnetic resonance (EPR) dosimetry is widely employed for radiation measurements with several compounds such as ammonium tartrate [1][2][3][4][5], lithium formate [6], dithionates, [7], phenolic compounds [8][9][10][11][12] and sugar [13,14] and others [15][16][17][18][19]. However, crystalline L-α-alanine is the most adopted material and is formally accepted as a secondary standard for high-dose measurements (kGy) and transfer dosimetry [20][21][22][23][24][25][26][27][28][29][30].…”