Characterization of Polysaccharides from Wild Edible Mushrooms from Thailand and Their Antioxidant, Antidiabetic, and Antihypertensive Activities

Kaewnarin, Khwanta; Suwannarach, Nakarin; Kumla, Jaturong; Choonpicharn, Sadabpong; Tanreuan, Keerati; Lumyong, Saisamorn

doi:10.1615/intjmedmushrooms.2020034092

Cited by 16 publications

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“…The dry matter of an edible mushroom is generally composed of protein (15–35%), carbohydrates (35–70%), essential fatty acids (less than 5%), as well as traces of vitamins and minerals (Barros et al 2008 ; Valverde et al 2015 ; Niego et al 2021a ). They are also known to have antioxidant, antimicrobial, anticancer, and immunomodulatory properties (De Silva et al 2012 ; Kaewnarin et al 2016 , 2020 ; Valverde et al 2015 ; Hyde et al 2019 ). Traditionally, fungal mycelia have only been used as flavor and color modifiers in fermented foods such as blue cheese, red mold rice, soy sauce and tempeh (Hyde et al 2019 ; Ahmad et al 2020 ).…”

Section: Mycelium-based Materialsmentioning

confidence: 99%

Ten decadal advances in fungal biology leading towards human well-being

et al. 2022

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Fungi are an understudied resource possessing huge potential for developing products that can greatly improve human well-being. In the current paper, we highlight some important discoveries and developments in applied mycology and interdisciplinary Life Science research. These examples concern recently introduced drugs for the treatment of infections and neurological diseases; application of –OMICS techniques and genetic tools in medical mycology and the regulation of mycotoxin production; as well as some highlights of mushroom cultivaton in Asia. Examples for new diagnostic tools in medical mycology and the exploitation of new candidates for therapeutic drugs, are also given. In addition, two entries illustrating the latest developments in the use of fungi for biodegradation and fungal biomaterial production are provided. Some other areas where there have been and/or will be significant developments are also included. It is our hope that this paper will help realise the importance of fungi as a potential industrial resource and see the next two decades bring forward many new fungal and fungus-derived products.

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Section: Mycelium-based Materialsmentioning

confidence: 99%

Ten decadal advances in fungal biology leading towards human well-being

et al. 2022

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“…DPPH analysis is widely used to assess the scavenging of free radicals (Wang et al., [ 27 ] ). The scavenging of DPPH radicals was much lower for REP fractions than for Vc (Figure 3C).…”

Section: Resultsmentioning

confidence: 99%

“…The scavenging of DPPH radicals of the crude extraction of polysaccharide of R. extremiorientalis is 10 mg g −1 (only about 1%). [ 19 ]…”

Section: Resultsmentioning

confidence: 99%

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Extraction, Bioactive Composition, and Antioxidant Activity of Polysaccharides from the Mushroom Rugiboletus extremiorientalis

Guo

Guo²,

et al. 2022

Starch Stärke

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The wild, edible mushroom Rugiboletus extremiorientalis has an excellent taste and also medicinal effects, and is very popular in China. In this study, hot water extraction is used to isolate polysaccharides from R. extremiorientalis fruiting bodies, and response surface methodology is used to optimize the extraction conditions in terms of temperature, liquid–solid ratio, and time. The crude extract (REP) is purified in turn by DEAE‐52 chromatography and Sephadex G‐100 chromatography, resulting in three fractions (REP‐1, REP‐2, and REP‐3) with recovery rates of 16.7%, 57.65%, and 6.63%, respectively. In vitro antioxidant activity is highest for REP‐2, and the subsequent research is therefore focused on that fraction. High‐performance liquid chromatography reveals that REP‐2 is comprised of fucose, arabinose, galactose, glucose, xylose, and mannose. Fourier‐transform infrared spectroscopy of REP‐2 indicates the presence of functional groups typical for polysaccharides. High‐performance gel filtration chromatography indicates the REP‐2 has a molecular weight of 342.4 kDa. The results of this study provide a foundation for future research concerning the antioxidant activity of polysaccharides in R. extremiorientalis.

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“…Polysaccharides also are ideal for the treatment of diabetes since they present diverse biological activities and are low cost as therapeutic applications (Alzahrani, 2017;Nie et al, 2019). Protein-polysaccharides complexes from mushrooms possess antihyperglycemic, antilipidemic, and antioxidant properties, making them ideal for the treatment of diabetes (Kaewnarin et al, 2020). Agaricus brasiliensis mushroom variety is rich in protein and polysaccharides, especially the β-glucans variety making it ideal in the treatment of diabetes.…”

Section: Epistemological On Protein-polysaccharide Complexes Treatment Of Diabetesmentioning

confidence: 99%

Epistemological Assumption: Understanding Protein Polysaccharide Complexes in Improving Diabetes Treatment

Alzahrani¹,

Pinto²

2021

NRFHH

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Embracing the philosophical condition of epistemology in research has led to identifying and understanding the meaning and nature of diabetes and the use of protein-polysaccharides complexes in the treatment of diabetes. The research approach is purely qualitative; thereby, postmodern epistemological assumptions were made from the theory of knowledge on diabetes, its conditions and symptoms, effects, protein and polysaccharides characteristics. The research develops knowledge on using protein-polysaccharides obtained mainly from plant species like mushrooms and pumpkins generated from credible and valid knowledge connected from observable justification, beliefs and truths from scholarly material. In the process, knowledge has been created identifying that protein-polysaccharides complexes contain polysaccharides that have proven to possess hypoglycaemic activity that reduces hyperglycaemia leading to an increase in insulin secretion and reduction of blood glucose.

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Characterization of Polysaccharides from Wild Edible Mushrooms from Thailand and Their Antioxidant, Antidiabetic, and Antihypertensive Activities

Cited by 16 publications

References 0 publications

Ten decadal advances in fungal biology leading towards human well-being

Ten decadal advances in fungal biology leading towards human well-being

Extraction, Bioactive Composition, and Antioxidant Activity of Polysaccharides from the Mushroom Rugiboletus extremiorientalis

Epistemological Assumption: Understanding Protein Polysaccharide Complexes in Improving Diabetes Treatment

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