This paper presents an experimental study on the structural performance of 26 composite slab specimens having trapezoidal and dovetail profiles. The influence of the span, details of the end anchorage, and cross -sectional depth on the mechanical performance and failure modes of the specimens was discussed. The effects of the thickness of the profiled steel sheets and additional reinforcement of the bottom on the longitudinal shear bearing capacity of long -span dovetail-profiled composite slabs were also investigated. Research on long-span composite slabs accounting for different details of the end anchorage and steel profiles is limited in the literature. The test results indicated that the end anchorage can significantly improve the mechanical performance and ultimate bearing capacity of composite slabs, whereas additional reinforcement and thick profiled steel sheets can slightly increase their bearing capacity. The test results also showed that, in long-span flooring systems, dovetail-profiled composite slabs have a higher load bearing capacity than trapezoidal-profiled composite slabs.