Characterization of skin Port‐Wine Stain and Hemangioma vascular lesions using Doppler <scp>OCT</scp>

Latrive, Anne; Teixeira, L.R.C.; Gomes, Anderson S. L.; Zezéll, Denise Maria

doi:10.1111/srt.12253

Cited by 23 publications

(17 citation statements)

References 28 publications

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“…13,14 Troilius et al 15 first measured PWSs with a highresolution 20-MHz US system, in an attempt to correlate the depth of the PWS vessels with various anatomic locations. Latrive et al 16 Thickening, a cobblestone pattern, and nodularity are found in about 40% of patients with advancing aging, which may result in a pulsed tunable dye laserresistant lesion. 18 Therefore, in this study, we categorized PWS cases into 4 groups: nodular, thickened, flattened, and acquired, according to the International Society for the Study of Vascular Anomalies.…”

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confidence: 99%

High‐Frequency Ultrasound Investigation of Port‐Wine Stains: Hemodynamic Features Revealed By 10‐ and 22‐MHz Transducers

Gong

et al. 2018

J of Ultrasound Medicine

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Objectives The hemodynamics of the ultrasound (US) features of port‐wine stains (PWSs) have not been reported. The purpose of this study was to evaluate the high‐frequency US findings of PWSs. Methods We retrospectively reviewed 98 PWS cases and categorized them into 4 groups based on clinical manifestations and pathologic findings (14 nodular, 28 thickened, 52 flattened, and 4 acquired). We evaluated the US findings with 10‐ and 22‐MHz transducers. Results For nodular PWSs, the mean thickened skin ± SD was 0.6 ± 0.5 mm, and the nodule thickness was 5.7 ± 3.3 mm; 63.6% of skin lesions showed vessel density of 2.16 ± 0.93/cm2 with venous flow of 4.6 ± 1.1 cm/s, and all nodules showed vessel density of 6.14 ± 1.92/cm2 with arterial and venous flow of 26.6 ± 17.9 and 9.9 ± 5.1 cm/s, respectively. The thickened skin of the thickened type was 1.4 ± 2.7 mm; 76.5% of skin lesions showed vessel density of 3.81 ± 1.98/cm2 with venous flow 4.6 ± 2.1 cm/s. The thickened skin of 36 flattened lesions was 0.1 ± 0.1 mm; 91.7% of skin lesions showed vessel density of 1.08 ± 0.28/cm2. The thickened skin of 4 acquired lesions was 0.7 ± 0.4 mm; 50% showed vessel density of 1.08 ± 0.28/cm2. The thickened skin and vessel density of nodular and thickened PWSs were thicker and higher than those of the flattened ones. The 22‐MHz transducer produced clearer contrast and higher vessel density than the 10‐MHz transducer. Conclusions These results showed differences in US findings of PWSs, which may be useful for clinical diagnosis.

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confidence: 99%

High‐Frequency Ultrasound Investigation of Port‐Wine Stains: Hemodynamic Features Revealed By 10‐ and 22‐MHz Transducers

Gong

et al. 2018

J of Ultrasound Medicine

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“…Angiographic OCT based on flow characteristics provides additional vascular information within tissue, such as diameter, shape and distribution of blood vessels and their perfusion. Angiographic OCT has been applied to detecting abnormal vasculature of skin lesions such as port-wine stain (PWS) and basal cell carcinoma (BCC) [24][25][26].…”

Section: Introductionmentioning

confidence: 99%

Dermoscopy guided dark-field multi-functional optical coherence tomography

Kwon

Yoon

Kim

et al. 2017

Biomed. Opt. Express

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Dermoscopy is a skin surface microscopic technique allowing specular reflection free observation of the skin, and has been used to examine pigmented skin lesions. However, dermoscopy has limitations in providing depth information due to lack of 3D resolution. In order to overcome the limitations, we developed dermoscopy guided multi-functional optical coherence tomography (MF-OCT) providing both high-contrast superficial information and depth-resolved structural, birefringent, and vascular information of the skin simultaneously. Dermoscopy and MF-OCT were combined by using a dichroic mirror, and dark-field configuration was adapted for MF-OCT to reduce specular reflection. After characterization, dermoscopy guided MF-OCT was applied to several human skin lesions such as the scar, port-wine stain (PWS) as well as the normal skin for demonstration. Various features of the scar and PWS were elucidated by both dermoscopy and MF-OCT. Dermoscopy guided MF-OCT may be useful for evaluation and treatment monitoring of skin lesions in clinical applications. Reinhold, "The sensitivity and specificity of optical coherence tomography for the assisted diagnosis of nonpigmented basal cell carcinoma: an observational study," Br. J. Dermatol. 173(2), 428-435 (2015). 28. A. J. Coleman, G. P. Penney, T. J. Richardson, A. Guyot, M. J. Choi, N. Sheth, E. Craythorne, A. Robson, and R. Mallipeddi, "Automated registration of optical coherence tomography and dermoscopy in the assessment of sub-clinical spread in basal cell carcinoma," Comput.

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“…4,6 Optical imaging has been used to study PWB vascular characteristics in a limited number of patients. [8][9][10][11][12] Optical coherence tomography (OCT) was adapted for dermatology in 1997 13 to diagnose nonmelanoma skin cancers and actinic keratoses, but also can have utility for the evaluation of cutaneous vascular lesions. 14 Unlike Doppler OCT, which is based on phasesensitive imaging, dynamic OCT (D-OCT) is based on speckle variance analysis.…”

Section: Introductionmentioning

confidence: 99%

Vascular characteristics of port wine birthmarks as measured by dynamic optical coherence tomography

Mehrabi

Holmes

Abrouk

et al. 2021

Journal of the American Academy of Dermatology

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Background: Port wine birthmarks (PWBs) are congenital capillary malformations. Vessel characteristics, such as diameter and depth, may impact presentation and outcomes. They can be imaged using dynamic optical coherence tomography, a high-resolution, noninvasive imaging method.Purpose: We conducted a cross-sectional observational study to measure in vivo vascular characteristics as a function of PWB color.Methods: Patients undergoing treatment for PWB were recruited from 3 sites. PWBs were classified by color. Dynamic optical coherence tomography images with calculations were obtained.Results: One hundred eight patients were enrolled. Mean age correlated with PWB color, with birthmarks being lighter in younger patients and darker in older patients (P \.01). Mean superficial plexus depth was significantly shallower in purple PWBs than in pink PWBs. Color was not associated with significant differences in mean superficial vessel density or diameter. Among pink PWBs, each 10-year increase in age was associated with a 10.6-m increase in superficial plexus depth. Among purple PWBs, each 10-year increase in age was associated with a 16.2-m reduction in superficial plexus depth. In lesions without prior treatment, vessel density was 12.7% lower in purple PWBs than in pink PWBs.Conclusion: Superficial vessels of purple PWBs were significantly closer to the epidermis than those of pink PWBs, which might impact optimal laser parameters.

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Characterization of skin Port‐Wine Stain and Hemangioma vascular lesions using Doppler OCT

Abstract: We show a significant difference between the vascular characteristics of the studied PWS and hemangiomas lesions. We believe that OCT complemented by Doppler OCT could be a promising method for future non-invasive diagnosis and monitoring of some vascular lesions.

Cited by 23 publications

References 28 publications

High‐Frequency Ultrasound Investigation of Port‐Wine Stains: Hemodynamic Features Revealed By 10‐ and 22‐MHz Transducers

High‐Frequency Ultrasound Investigation of Port‐Wine Stains: Hemodynamic Features Revealed By 10‐ and 22‐MHz Transducers

Dermoscopy guided dark-field multi-functional optical coherence tomography

Vascular characteristics of port wine birthmarks as measured by dynamic optical coherence tomography

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