Schisandra macrocarpa
Lin & Shui, 2011, belongs to the family Schisandraceae and was recently added to the List of National Key Protected Wild Plants in China. We report the complete chloroplast (cp) genome of
S. macrocarpa
using Illumina Nova-Seq 6000 platform. The results showed that the cp genome size of
S. macrocarpa
was 144,288 bp, which contained a small single-copy (SSC) region (17,862 bp), a large single-copy (LSC) region (93,332 bp), and a pair of inverted repeat (IR) regions (16,547 bp). The cp genome has 40% overall GC content. Annotated genes were 128 in all, including 83 protein-coding genes, eight rRNA genes, and 37 tRNA genes. The phylogenetic analysis showed that
S. macrocarpa
was closely related to
S. propinqua
subsp
. sinensis
. This work contributes to the conservation of this species and the evolutionary analysis of Schisandraceae.