Characterization of the mechanical properties for cranial bones of 8-week-old piglets: the effect of strain rate and region

Li, Zhigang; Wang, Guangliang; Ji, Cheng; Jiang, Jinzhong; Wang, Jiawei; Wang, Jian

doi:10.1007/s10237-019-01169-7

Cited by 9 publications

(4 citation statements)

References 30 publications

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“…Significant progress has been made in the biomechanical study of pig vertebrae in recent years [10]. Experimental tests, including axial and radial tests, have been employed to determine the material properties, which exhibit an anisotropic material behavior [11,12]. This characterization also allowed a comparative study of the various properties of porcine bones compared to humans and other species [13,14].…”

Section: Introductionmentioning

confidence: 99%

Characterization of Pig Vertebrae under Axial Compression Integrating Radiomic Techniques and Finite Element Analysis

Hernández-Salazar,

Chamorro,

González-Estrada

2024

Inventions

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The study of pig bones, due to their similarity with human tissues, has facilitated the development of technological tools that help in the diagnosis of diseases and injuries affecting the skeletal system. Radiomic techniques involving medical image segmentation, along with finite element analysis, enable the detailed study of bone damage, loss of density, and mechanical functionality, which is a significant advancement in personalized medicine. This study involves conducting experimental tests on L3–L6 pig vertebrae under axial loading conditions. The mechanical properties of these vertebrae are analyzed, and the maximum loads they can sustain within the elastic range are determined. Additionally, three-dimensional models are generated by segmenting computerized axial tomography (CAT) scans of the vertebrae. Digital shadows of the vertebrae are constructed by assigning an anisotropic material model to the segmented geometries. Then, finite element analysis is performed to evaluate the elastic characteristics, stress, and displacement. The findings from the experimental data are then compared to the numerical model, revealing a strong correlation with differences of less than 0.8% in elastic modulus and 1.53% in displacement. The proposed methodology offers valuable support in achieving more accurate medical outcomes, employing models that serve as a diagnostic reference. Moreover, accurate bone modeling using finite element analysis provides valuable information to understand how implants interact with the surrounding bone tissue. This information is useful in guiding the design and optimization of implants, enabling the creation of safer, more durable, and biocompatible medical devices that promote optimal osseointegration and healing in the patient.

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Section: Introductionmentioning

confidence: 99%

Characterization of Pig Vertebrae under Axial Compression Integrating Radiomic Techniques and Finite Element Analysis

Hernández-Salazar,

Chamorro,

González-Estrada

2024

Inventions

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“…Considering that the anatomical structure of piglet head is similar to that of children, 18 and a lot of material properties for components of the piglet head have been obtained and attempted to correspond to children, 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 the piglet head was generally used as a surrogate to study the biomechanical response and mechanism of pediatric head injury. Compared with the experiments conducted on the piglet heads, 27 , 28 , 29 , 30 the FE model of a piglet head can capture more responses under different impact conditions, which can be considered as a supplement to the experiment.…”

Section: Introductionmentioning

confidence: 99%

Development and global validation of a 1-week-old piglet head finite element model for impact simulations

et al. 2023

Chinese Journal of Traumatology

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“…In some studies, researchers also used constitutive models for the simulation of nano-indentation test 21 and tensile test. 22…”

Section: Introductionmentioning

confidence: 99%

“…In some studies, researchers also used constitutive models for the simulation of nano-indentation test 21 and tensile test. 22 Although JC, CS and ZA models consider the strain rate dependence of the plastic curve, the lack of the predictability of the individual JC and CS models and non-applicability of the ZA model limit their use in the bone cutting simulations. Because, to develop the ZA model, the dislocation mechanics involved in the face centred cubic (FCC), body centred cubic (BCC) and hexagonal close packed (HCP) crystalline structure of the metals need to be used, 23 the model cannot be developed for bone.…”

Section: Introductionmentioning

confidence: 99%

An in-silico bone drilling protocol to control thrust forces using finite element analysis coupled with the constitutive models

Prasannavenkadesan

Pandithevan

2022

Proceedings of the Institution of Mechanical Engineers, Part C:

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In orthopaedic surgeries, drilling through bone is most widely used to fix the plates and implants. The uncontrolled large thrust forces generated during bone drilling cause micro-crack, and fragmentation around the local host bone which further loosen the implant and fixation. Owing to the experimental limitation and the risk of infection in handling the bone specimens, conducting experiments with all possible combinations of parameter values and selecting the suitable combination is largely limited. So in this paper, finite element analysis coupled with the constitutive models was used to early predict the thrust forces generated in the surgical bone drilling process. The constitutive models developed in the earlier study, namely, Johnson–Cook, Cowper–Symonds, and Johnson–Cook combined with Cowper–Symonds that consider the strain rate dependence of plastic curve were used for the simulations. Results revealed that the trends of the thrust force values predicted from the constitutive models matched well with the experiments. However, the study showed that the Johnson–Cook model combined with the Cowper–Symonds model predicted the thrust forces with a maximum error of only 9.51% followed by the Johnson–Cook model and Cowper–Symonds model with 15.83% and 21.89%, respectively. The outcomes of the study can be used to predict the thrust forces generated in the bone drilling process, and thus, suitable parameters values can be selected to avoid the mechanical damages around the bone drilling site. The outcomes can also be used to plan and rehearse the in-silico bone drilling trials with any combinations of parameter values before performing the actual surgery.

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Characterization of the mechanical properties for cranial bones of 8-week-old piglets: the effect of strain rate and region

Cited by 9 publications

References 30 publications

Characterization of Pig Vertebrae under Axial Compression Integrating Radiomic Techniques and Finite Element Analysis

Characterization of Pig Vertebrae under Axial Compression Integrating Radiomic Techniques and Finite Element Analysis

Development and global validation of a 1-week-old piglet head finite element model for impact simulations

An in-silico bone drilling protocol to control thrust forces using finite element analysis coupled with the constitutive models

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