Characterization of Ti-35Nb alloy surface modified by controlled chemical oxidation for surgical implant applications

Abstract

Titanium-Niobium alloys have been studied for biomedical applications due to their satisfactory biocompatibility. In order to improve the long-term implantation, surface modification techniques have been developed to generate suitable topography, roughness, chemical composition, surface energy, etc. Considering this approach, the present work aimed to characterize Titanium-35Niobium (Ti-35Nb) surface modified by controlled chemical oxidation. Ti-35Nb (wt%) substrates were processed by powder metallurgy. The powders were mechanically mixed, uniaxially cold pressed and sintering at 1300ºC/2h. Then, the sintered substrates were immersed in a solution consisting of equal volumes of concentrated H 2 SO 4 and 30% aqueous H 2 O 2 for 4 hours at room temperature under continuous agitation. Sample characterizations were performed by scanning electron microscopy, profilometry, contact angle measurement, X-ray diffraction, and X-ray photoelectron spectroscopy. The results showed that the samples exhibited a microporous structure with micro-roughness on surface, and the β-Ti phase was stabilized by complete niobium atoms diffusion in titanium matrix. In addition, the chemical treatment successfully modified the Ti-35Nb surface with micropore formation and enhancement of hydrophilic feature and TiO 2 and Nb 2 O 5 layer, which can improve the biocompatibility of TiNb alloy implants.

Mechanism of Fatigue Crack Growth in Biomedical Alloy Ti-27Nb

“…In titanium alloys, Ti-27Nb has attracted attention as a promising material for bone implants because of high fatigue strength, non-corrosiveness, non-toxicity, good mechanical properties, and superior biocompatibility [11,12]. Ti-27Nb is less ductile, having 12% less ultimate strength as compared with its counterpart Ti-6Al-4V.…”

Desenvolvimento de filmes de TiO2 produzidos por tratamento eletroquímico sobre a liga Ti6Al4V: sua caracterização físico-química e mecânica

“…Alguns estudos mostram que uma forma de abaixar mais o módulo de elasticidade nas ligas de Ti é através da adição de nióbio e tântalo. Com esses elementos pode-se conseguir um módulo E ≈ 55 GPa [9][10][11].…”

“…Alguns trabalhos têm demonstrado que estruturas microporosas (< 20 µm) de TiO 2 produzidas na superfície do titânio e suas ligas podem favorecer a osteointegração e prevenir a falha precoce do implante. De acordo com esses trabalhos, isso ocorre devido ao espaço que esses poros proporcionam às células ósseas, o que favorece à vascularização e crescimento do tecido ósseo, levando ao travamento mecânico entre prótese e osso [11]. KOKUBO e YAMAGUCHI [15] propuseram em seu trabalho que a formação de apatita sobre o implante ocorrerá, em meio fisiológico, em função do potencial Zeta na sua superfície.…”

Study of the influence of titanium and niobium particle size on the Ti35Nb alloy production with controlled porosity

“…Vanadium and aluminum are currently the elements most often added to titanium alloys and act as phase stabilizers [3], however, it has been shown that these elements can be harmful to human health, because the gradual release of cytotoxic elements such as aluminum (Al) and vanadium (V) pose a high risk of long-term health problems including Alzheimer's disease, osteomalacia, and other neurological conditions [4,5]. Thus, the use of niobium (Nb), a betagenic element (β-Ti phase stabilizer), has been emerging and showing great potential, as it is able to produce alloys with elastic modulus closer to the human bone and improved workability due to their body-centered cubic microstructure, in comparison to commercial pure Ti and Ti6Al4V alloy [5][6][7][8][9][10].…”