Characterization of titanium surfaces with calcium and phosphate and osteoblast adhesion

Feng, Bo; Weng, Jie; Yang, Bang Cheng; Qu, Shuxin; Zhang, X.D.

doi:10.1016/j.biomaterials.2003.10.044

Cited by 143 publications

(89 citation statements)

References 24 publications

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“…No C-N-related peak was revealed for original titanium disks without AA-GDP pretreatmentdespite being immersed in collagen solution, thereby demonstrating a lack of collagen grafting capability (Fig. 5) 22) . It has been suggested that osteoblast differentiation is promoted in glow discharge-treated titanium plates 13) .…”

Section: Discussionmentioning

confidence: 98%

Type I Collagen Grafting on Titanium Surfaces Using Low-temperature Glow Discharge

Chang¹,

Ou²,

Lee³

et al. 2008

Dent. Mater. J.

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To improve the bioactivity of titanium surfaces, glow discharge was used to facilitate collagen grafting on titanium disks. Titanium test specimens were pre-treated by glow discharge fed with a mixture of argon and allylamine (AA) gases. Treated titanium disks were then grafted with type I collagen using glutaraldehyde (GA) as a crosslinking agent. The surfaces of collagen-grafted titanium disks were evaluated using scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and X-ray photoelectron spectroscopy (XPS). MG-63 osteoblast-like cells were cultured on the grafted titanium surfaces to examine the effect of collagen grafting in terms of cell morphology. Our results demonstrated that collagen component elements could be detected on the titanium surfaces. Morphology of the cells on the surfaces of collagen-grafted titanium disks indicated differentiation. These findings showed that type I collagen could be successfully grafted onto titanium surfaces using glow discharge technology, with enhanced biofunctionality demonstrated on osteoblastic cells.

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Section: Discussionmentioning

confidence: 98%

Type I Collagen Grafting on Titanium Surfaces Using Low-temperature Glow Discharge

Chang¹,

Ou²,

Lee³

et al. 2008

Dent. Mater. J.

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“…Moreover, having calcium element in the chemical composition of FHA coating can be helpful on the cellular behavior, as it improves the chemical signaling of the cells and absorbs fibronectin and vitronectin proteins which are crucial elements on the biological function of the cells. 36 The AZ91 (a), MAO (d), and FHA/MAO coated (g) samples were implanted into the greater trochanter of rabbits and the surgery images are presented in Fig. 4.…”

mentioning

confidence: 99%

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Razavi

Fathi

Savabi

et al. 2015

Materials Science and Engineering: C

103

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Although magnesium (Mg) is a unique biodegradable metal which possesses mechanical property similar to that of the natural bone and can be an attractive material to be used as orthopedic implants, its quick corrosion rate restricts its actual clinical applications. To control its rapid degradation, we have modified the surface of magnesium implant using fluoridated hydroxyapatite (FHA: Ca10(PO4)6OH2 − xFx) through the combined micro-arc oxidation (MAO) and electrophoretic deposition (EPD) techniques, which was NOT THE PUBLISHED VERSION; this is the author's final, peer-reviewed manuscript. The published version may be accessed by following the link in the citation at the bottom of the page. 2015): pg. 21-27. DOI. This article is © Elsevier and permission has been granted for this version to appear in e-Publications@Marquette. Elsevier does not grant permission for this article to be further copied/distributed or hosted elsewhere without the express permission from Elsevier. Materials Science and Engineering: C, Vol 48 (March3 presented in our previous paper. In this article, the biocompatibility examinations were conducted on the coated AZ91 magnesium alloy by implanting it into the greater trochanter area of rabbits. The results of the in vivo animal test revealed a significant enhancement in the biocompatibility of FHA/MAO coated implant compared to the uncoated one. By applying the FHA/MAO coating on the AZ91 implant, the amount of weight loss and magnesium ion release in blood plasma decreased. According to the histological results, the formation of the new bone increased and the inflammation decreased around the implant. In addition, the implantation of the uncoated AZ91 alloy accompanied by the release of hydrogen gas around the implant; this release was suppressed by applying the coated implant. Our study exemplifies that the surface coating of magnesium implant using a bioactive ceramic such as fluoridated hydroxyapatite may improve the biocompatibility of the implant to make it suitable as a commercialized biomedical product.

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“…Particularly on surface chemistry, it has been shown that the initial cell adhesion onto the surfaces involved in many kinds of biological and chemical interactions relating to calcium, phosphorus, carbon, oxygen and nitrogen elements. 29 This result may imply that the more phosphorus found the better early cell attachment. Though, the number of attached cells was similar at 1 h. There are several studies demonstrating the correlation of cell attachment and osteogenic differentiation ability.…”

Section: Discussionmentioning

confidence: 99%

Surface properties and early murine pre-osteoblastic cell responses of phosphoric acid modified titanium surface

Osathanon

Sawangmake

Ruangchainicom

et al. 2016

Journal of Oral Biology and Craniofacial Research

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Characterization of titanium surfaces with calcium and phosphate and osteoblast adhesion

Cited by 143 publications

References 24 publications

Type I Collagen Grafting on Titanium Surfaces Using Low-temperature Glow Discharge

Type I Collagen Grafting on Titanium Surfaces Using Low-temperature Glow Discharge

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Surface properties and early murine pre-osteoblastic cell responses of phosphoric acid modified titanium surface

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