Characterization of Urea Biosensor Based on the Immobilization of Bacteria Proteus Mirabilis in Interaction with Iron Oxide Nanoparticles on Gold Electrode

Braham, Y.; Barhoumi, Houcine; Maaref, Abderrazak; Bakhrouf, Amina; Heywang, C.; Bouhacina, Tauria Cohen; Jaffrézic‐Renault, Nicole

doi:10.4172/2155-6210.1000160

Cited by 2 publications

(2 citation statements)

References 27 publications

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“…Experimental data were subsequently fitted to a simple Randles circuit presented in Fig. 4c, which comprised a parallel combination of solution resistance (R s ), charge transfer resistance (R), constant phase element (CPE) and Warburg diffusion element (W s ) [75,76]. The constant phase element replaces typically used doublelayer capacitance, showing that the surfaces of both electrodes behave as imperfect capacitors.…”

Section: 4 Electrochemical Impedance Analysismentioning

confidence: 99%

Self-supporting carbon nanotube films as flexible neural interfaces

Krukiewicz

Janas

Vallejo-Giraldo

et al. 2019

Electrochimica Acta

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Advances in neural interface technologies have sought to identify electroactive materials that are able to translate neural depolarisation events into digital signals or modulate neural firing through ionic or electrical stimulation with greater efficiency. An ideal material for neural recording and/or stimulation should possess low electrical impedance coupled with a high cathodic charge storage capacity (CSC C ), charge injection capacity (CIC) and electroactive surface area (ESA), as well as optimal mechanical biomimicry. In this study, we present the robustness of self-supporting CNT films as neural interfaces, combining advantageous electrical and mechanical properties with high cytocompatibility. Films were observed to possess a high CSC C (29.95 ± 0.91 mC cm -2 ), CIC (352 ± 5 µC V -1 cm -2 ) and ESA (0.908 ± 0.053 cm 2 ), low impedance (110 Ω at 1 kHz), low resistance (75 ± 13 Ω) and high capacitance (378 ± 9 µF cm -2 ), and outperformed Pt control electrodes. Self-supporting CNT films were also found to facilitate neuron growth and decrease the presence of reactive astrocytes in a mixed neural cell population. Self-standing CNT films were shown to be promising materials for the design of flexible and cytocompatible neural interfaces.

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Section: 4 Electrochemical Impedance Analysismentioning

confidence: 99%

Self-supporting carbon nanotube films as flexible neural interfaces

Krukiewicz

Janas

Vallejo-Giraldo

et al. 2019

Electrochimica Acta

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“…Randles circuit was employed (Fig.5A inset), comprising a parallel combination of solution resistance (R 1 ), charge transfer resistance (R 1 ), constant phase element (CPE) and Warburg diffusion element (W) [68,69]. The model resulted in a good fit (χ 2 between 0.85  10 -4 and 7.09  10 -4 ) between the experimental and simulated data (Tab.1).…”

Section: 5 Electrochemical Impedance Analysismentioning

confidence: 98%

Electrodeposited poly(3,4-ethylenedioxypyrrole) films as neural interfaces: Cytocompatibility and electrochemical studies

Krukiewicz

Kowalik

Czerwińska-Główka

et al. 2019

Electrochimica Acta

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Conducting polymers have been extensively reported as promising coating materials for applications involving interactions with electrically excitable tissues. Specifically, metal electrodes functionalized with conducting polymer coatings have been employed as biointerface presenting tailored properties to promote electrode integration as well as chronic functionality. Currently, polypyrrole (PPy) and poly(3,4-ethylenedioxythiophene) (PEDOT) represent the most extensively studied conducting polymers, exhibiting favourable electrochemical properties and biocompatibility. In this paper, we study electrodeposited poly(3,4-ethylenedioxypyrrole) (PEDOP), a conducting polymer which is structurally related to both PEDOT and PPy, and is expected to outperform its "parent" polymers in terms of electrochemical properties and biocompatibility. The performance of PEDOP doped with chloride/phosphate, p-toluenesulfonate or polystyrene sulfonate was subsequently investigated to assess the efficacy of these ionic dopants in promoting electrochemical stability and neural cytocompatibility. Electrodeposited PEDOP films exhibited a high charge storage capacity (50.07 ± 6.96 mC cm-2), charge injection capacity (203 ± 24 µC cm-2) and substantial stability (performance loss of 0.49 ± 0.06 % after 100 000 stimulation pulses). Furthermore, PEDOP films promoted enhanced neuron outgrowth and viability relative to control substrates. In particular, PEDOP/PTS was shown to increase the average neurite length three times when compared with cells cultured on bare Pt control. Consequently, due to its favourable electrochemical characteristics together with high neural cytocompatibility, PEDOP can be indicated as a promising alternative to PPy and PEDOT in the field of neural science.

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Characterization of Urea Biosensor Based on the Immobilization of Bacteria Proteus Mirabilis in Interaction with Iron Oxide Nanoparticles on Gold Electrode

Cited by 2 publications

References 27 publications

Self-supporting carbon nanotube films as flexible neural interfaces

Self-supporting carbon nanotube films as flexible neural interfaces

Electrodeposited poly(3,4-ethylenedioxypyrrole) films as neural interfaces: Cytocompatibility and electrochemical studies

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