Characterization of Various Groups of Drugs Users. Highlights on Legal Highs Users

ANGHEL, DANIELA-MĂDĂLINA CIUCĂ

doi:10.31925/farmacia.2023.1.3

Cited by 2 publications

(2 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The findings from this research are in line with the outcomes of other studies assessing the cardiotoxicity of various drugs. In this regard, previous research outlined that alcohol users are more likely to develop cardiac events than other drug users [ 136 ].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Understanding the Mechanisms of Action and Effects of Drugs of Abuse

et al. 2023

View full text Add to dashboard Cite

Aim. Drug abuse and addiction are major public health concerns, with millions of people worldwide affected by the negative consequences of drug use. To better understand this complex issue, a review was conducted to examine the mechanisms of action and effects of drugs of abuse, including their acute and chronic effects, the symptoms of abstinence syndrome, as well as their cardiovascular impacts. Methods. The analyzed data were obtained after surveying an electronic database, namely PubMed, with no time limit, grey literature sources, and reference lists of relevant articles. Results. The review highlights the different categories of drugs of abuse, such as opioids, stimulants, depressants, hallucinogens, and cannabis, and discusses the specific ways that each drug affects the brain and body. Additionally, the review explores the short-term and long-term effects of drug abuse on the body and mind, including changes in brain structure and function, physical health problems, and mental health issues, such as depression and anxiety. In addition, the review explores the effects of drug abuse on cardiovascular health, focusing on electrocardiogram changes. Moreover, the analysis of relevant literature also highlighted possible genetic susceptibility in various addictions. Furthermore, the review delves into the withdrawal symptoms that occur when someone stops using drugs of abuse after a period of chronic use. Conclusion. Overall, this review provides a comprehensive overview of the current state of knowledge on drug abuse and addiction. The findings of this review can inform the development of evidence-based prevention and intervention strategies to address this critical public health issue.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Recent findings outline the toxicity of cannabis on the cardiovascular system, the harmful effects on the cardiovascular system being associated with an increased risk of myocardial injury among cannabis users [135]. These findings are sustained by recent studies run on cannabis users [136].…”

Section: Particular Mechanismmentioning

confidence: 93%

Understanding the Mechanisms of Action and Effects of Drugs of Abuse

et al. 2023

View full text Add to dashboard Cite

show abstract

Patterns and Emerging Trends in Acute Poisoning with Substances of Abuse Used for Recreational Purposes in Adolescents: A Six-Year Multicentre Study

Turcu,

Lescaie,

Grama

et al. 2024

Life

View full text Add to dashboard Cite

This six-year multicentre study investigated acute intentional poisoning with substances of abuse in adolescents to identify changes and patterns in substance use. Data from 562 adolescents were collected from three paediatric poison centres in Romania between January 2017 and December 2022. This study analysed the epidemiological and sociodemographic characteristics of the adolescents, including age, gender, place of residence, history of substance abuse, psychiatric history, and history of institutionalised care. The findings revealed that cannabis and new psychoactive substances (NPSs) are the most commonly implicated substances, each with distinct profiles among adolescents. Cannabis was involved in 46.1% of cases, with a significant association with urban residency. NPSs were identified as the second most prevalent substance, accounting for 39.3% of cases. These were more prevalent in rural areas and among patients with psychiatric disorders. Cannabis and NPSs were also the most commonly implicated substances in acute intentional poisoning cases with substances of abuse. These substances have distinct profiles among adolescents, including age, gender, residency area, history of substance abuse, psychiatric history, and institutional care. These findings underscore the necessity of targeted public health interventions and integrated care approaches to address substance use and related mental health issues in adolescents.

show abstract

Characterization of Various Groups of Drugs Users. Highlights on Legal Highs Users

Cited by 2 publications

References 32 publications

Understanding the Mechanisms of Action and Effects of Drugs of Abuse

Understanding the Mechanisms of Action and Effects of Drugs of Abuse

Patterns and Emerging Trends in Acute Poisoning with Substances of Abuse Used for Recreational Purposes in Adolescents: A Six-Year Multicentre Study

Contact Info

Product

Resources

About