2023
DOI: 10.1002/yea.3910
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Characterizing a panel of amino acid auxotrophs under auxotrophic starvation conditions

Alisha G. Lewis,
Laurin Carmichael,
Rebecca Y. Wang
et al.

Abstract: Auxotrophic strains starving for their cognate nutrient, termed auxotrophic starvation, are characterized by a shorter lifespan, higher glucose wasting phenotype, and inability to accomplish cell cycle arrest when compared to a “natural starvation,” where a cell is starving for natural environmental growth‐limiting nutrients such as phosphate. Since evidence of this physiological response is limited to only a subset of auxotrophs, we evaluated a panel of auxotrophic mutants to determine whether these responses… Show more

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