2024
DOI: 10.1038/s44298-024-00022-8
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Characterizing changes in transcriptome and kinome responses in testicular cells during infection by Ebola virus

Andrew L. Webb,
Brayden G. Schindell,
Geoff Soule
et al.

Abstract: Ebola virus (EBOV) is able to persist and actively replicate in the reproductive tract of male disease survivors months or years after recovery from Ebola virus disease (EVD)1. Persistent EBOV infections are usually asymptomatic and can be transmitted sexually, but the host and viral factors that mediate these infections have not been characterized2,3. We investigated the interaction between host and viral factors during EBOV infection of the blood testis barrier (BTB), with a focus on Sertoli cells as a poten… Show more

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