The aerospace RF cable assembly is an important component for the propagation of space communication signals, which can achieve impedance matching and energy transmission of microwave signal transmission paths. In addition to the requirements for a wide frequency range, low insertion loss, and low standing wave as required for conventional RF cable components, it must also possess high reliability, spatial temperature resistance, vacuum high-power transmission, and other spatial adaptability capabilities. This article primarily discusses the damage to the insulation materials of cable components under space-limit temperatures and its impact on the performance of the cable components. The problem of deterioration and even failure of the performance of aerospace RF cable components in high and low-temperature alternating environments in space has been addressed through the adoption of corresponding measures.