Characterizing Potentially Inappropriate Prescribing of Proton Pump Inhibitors in Older People in Primary Care in Ireland from 1997 to 2012

Moriarty, Frank; Bennett, Kathleen; Cahir, Caitriona; Fahey, Tom

doi:10.1111/jgs.14528

Cited by 31 publications

(27 citation statements)

References 27 publications

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“…Proton pump inhibitors (PPIs) are widely used in this population, with a weighted prevalence estimate of 18.5% of community‐dwelling older adults using them in a 2010–11 cohort . The 2015 Beers Criteria recommend against the use of PPIs for longer than 8 weeks except in high‐risk individuals, but many clinicians may not be following this recommendation . This warning was based on the risks of Clostridium difficile infection (CDI) and bone loss and fractures.…”

Section: Important Side Effects Of Drugs Commonly Prescribed In Primamentioning

confidence: 99%

Common Drug Side Effects and Drug‐Drug Interactions in Elderly Adults in Primary Care

Merel

Paauw

2017

J American Geriatrics Society

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Prescribing medications, recognizing and managing medication side effects and drug interactions, and avoiding polypharmacy are all essential skills in the care of older adults in primary care. Important side effects of medications commonly prescribed in older adults (statins, proton pump inhibitors, trimethoprim-sulfamethoxazole and fluoroquinolone antibiotics, zolpidem, nonsteroidal antiinflammatory drugs, selective serotonin reuptake inhibitors, dipeptidyl peptidase 4 inhibitors) were reviewed. Important drug interactions with four agents or classes (statins, warfarin, factor Xa inhibitors, and calcium channel blockers) are discussed.

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Section: Important Side Effects Of Drugs Commonly Prescribed In Primamentioning

confidence: 99%

Common Drug Side Effects and Drug‐Drug Interactions in Elderly Adults in Primary Care

Merel

Paauw

2017

J American Geriatrics Society

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“…Various studies have shown that patients entering and leaving the hospital with continuous PPI prescriptions often do not have these medications reconciled and frequently receive log‐term treatment without proper indication . Long‐term PPI use is defined by various studies as 8 or more weeks of daily drug utilization . As the concerns related to adverse effects due to long‐term drug usage and the concern for inappropriate long‐term PPI therapy continue to increase, practice patterns in the discussed specialties seem to thus far be unaffected.…”

Section: Discussionmentioning

confidence: 99%

Practice patterns of reflux medication prescriptions in otolaryngology compared to other specialties

Luetzenberg

Jiang

2019

The Laryngoscope

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Objectives/Hypothesis To describe the trends in proton pump inhibitor (PPI) prescription rates and durations and compare them to those of H2‐receptor antagonists (H2RAs) between 2013 and 2016 in otolaryngology, gastroenterology, and family practice, following the increasing publications on PPI adverse effects and inappropriate prescribing. Study Design Retrospective review of publicly available Medicare Part D prescribing data. Methods PPI and H2RA prescription and beneficiary data were obtained through the Centers for Medicare and Medicaid Services website. For prescription rates, 30‐day fill counts were analyzed nationally and regionally per 10,000 Medicare members. Days supply per beneficiary was examined to show average prescription durations. Results were compared between otolaryngology, gastroenterology, and family practice. Medication‐related economic burden per year was calculated based on reported drug cost. Results From 2013 to 2016, PPI 30‐day fill counts remained stable, whereas H2RA prescription rates increased by up to 62% per 10,000 Medicare beneficiaries. The South consistently prescribed two to three times as much antireflux medication as the lowest prescribing region over time and across all three specialties. The days supply per beneficiary remained stable and ranged from an average of 128 to 203 days depending on the specialty. Antireflux medication‐related healthcare cost decreased steadily. Conclusions Despite numerous publications describing a multitude of adverse events and inappropriate prescribing patterns of PPIs in the past decade, prescription rates and durations per beneficiary have remained stable in the fields of otolaryngology, gastroenterology, and family practice. Additionally, H2RA prescriptions have increased from 2013 to 2016. Level of Evidence NA Laryngoscope, 130:321–327, 2020

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“…drugs worldwide [1][2][3][4]. A number of studies have suggested, however, that many patients are prescribed PPIs inappropriately [5][6][7][8].…”

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confidence: 99%

Long‐term use of proton pump inhibitors, dose–response relationship and associated risk of ischemic stroke and myocardial infarction

et al. 2017

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Characterizing Potentially Inappropriate Prescribing of Proton Pump Inhibitors in Older People in Primary Care in Ireland from 1997 to 2012

Abstract: 275Word count: 2614

Cited by 31 publications

References 27 publications

Common Drug Side Effects and Drug‐Drug Interactions in Elderly Adults in Primary Care

Common Drug Side Effects and Drug‐Drug Interactions in Elderly Adults in Primary Care

Practice patterns of reflux medication prescriptions in otolaryngology compared to other specialties

Long‐term use of proton pump inhibitors, dose–response relationship and associated risk of ischemic stroke and myocardial infarction

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