We present a detailed study of magnetic reconnection in a quasi-two-dimensional pulsed-power driven laboratory experiment. Oppositely directed magnetic fields (B ¼ 3 T), advected by supersonic, subAlfvénic carbon plasma flows (V in ¼ 50 km=s), are brought together and mutually annihilate inside a thin current layer (δ ¼ 0.6 mm). Temporally and spatially resolved optical diagnostics, including interferometry, Faraday rotation imaging, and Thomson scattering, allow us to determine the structure and dynamics of this layer, the nature of the inflows and outflows, and the detailed energy partition during the reconnection process. We measure high electron and ion temperatures (T e ¼ 100 eV, T i ¼ 600 eV), far in excess of what can be attributed to classical (Spitzer) resistive and viscous dissipation. We observe the repeated formation and ejection of plasmoids, consistent with the predictions from semicollisional plasmoid theory. DOI: 10.1103/PhysRevLett.118.085001 Magnetic reconnection is the rapid change of magnetic field topology in a plasma, accompanied by bulk heating and particle acceleration [1,2]. Reconnection is a ubiquitous process that occurs across a vast region of parameter space, including the collisionless plasmas at the heliopause [3] and the dense, hot plasmas deep in the solar convection zone [4,5]. Our understanding of magnetic reconnection has improved over the years thanks to dedicated laboratory experiments. In facilities like MRX [6][7][8] and TREX [9] the magnetic energy is much larger than the other plasma energy components. In contrast, laser-driven high energy density experiments are strongly driven-the kinetic and thermal energies are much larger than the magnetic energy [10,11], and reconnection heating is small [12].In this Letter we present experimental studies of high energy density magnetic reconnection driven by a new pulsed-power platform. The reconnection layer was created by the interaction of magnetized plasma flows in a quasi-2D geometry, which we studied using high resolution, nonperturbative measurements of the temperature, flow velocity, electron density, and magnetic field in the reconnection layer. The colliding plasma flows were supersonic (M s ∼ 1.6) but sub-Alfvénic (M A ∼ 0.7), and therefore the thermal and dynamic plasma betas (ratio of the thermal or ram pressure to the magnetic pressure) are close to unity (β th ∼ 0.7, β dyn ∼ 0.9). These parameters are significantly different from those found both in magnetically driven experiments, such as MRX, and in laser driven experiments, and we believe our experiments are the first to make a detailed study of this regime. We observed the formation of a reconnection layer with an aspect ratio of L=δ > 10, which existed for at least ten hydrodynamic flow times δ=V in , where L is the layer half length and δ is the layer half width [ Fig. 1(a)]. The annihilation of the magnetic flux caused strong plasma heating in the reconnection layer (T i ≈ 600 eV,ZT e ≈ 600 with T e ≈ 100 eV in a carbon plasma with average ionizationZ ≈ 6)...