Characterizing the rheological behaviors of non-Newtonian fluid via a viscoelastic component: Fractal dashpot

Su, Xianglong; Chen, Wen; Xu, Wenxiang

doi:10.1177/1687814017699765

Cited by 25 publications

(5 citation statements)

References 45 publications

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“…Moreover, the high viscosity of the polymer solution also suppresses the filling of the small cavities in the PDMS mold with polymer solution [ 26 ]. In addition, the apparent viscosity of all polymer solutions decreased when the shear rate increased, as shown in Figure 4 , so the centrifugation applied in this work facilitated the polymer solutions to be loaded into the MN molds [ 27 ].…”

Section: Resultsmentioning

confidence: 99%

HPMC/PVP K90 Dissolving Microneedles Fabricated from 3D-Printed Master Molds: Impact on Microneedle Morphology, Mechanical Strength, and Topical Dissolving Property

Chanabodeechalermrung,

Chaiwarit,

Chaichit

et al. 2024

Polymers

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Three-dimensional (3D) printing can be used to fabricate custom microneedle (MN) patches instead of the conventional method. In this work, 3D-printed MN patches were utilized to fabricate a MN mold, and the mold was used to prepare dissolving MNs for topical lidocaine HCl (L) delivery through the skin. Topical creams usually take 1–2 h to induce an anesthetic effect, so the delivery of lidocaine HCl from dissolving MNs can allow for a therapeutic effect to be reached faster than with a topical cream. The dissolving-MN-patch-incorporated lidocaine HCl was constructed from hydroxypropyl methylcellulose (HPMC; H) and polyvinyl pyrrolidone (PVP K90; P) using centrifugation. Additionally, the morphology, mechanical property, skin insertion, dissolving behavior, drug-loading content, drug release of MNs and the chemical interactions among the compositions were also examined. H51P2-L, H501P2-L, and H901P2-L showed an acceptable needle appearance without bent tips or a broken structure, and they had a low % height change (<10%), including a high blue-dot percentage on the skin (>80%). These three formulations exhibited a drug-loading content approaching 100%. Importantly, the composition-dependent dissolving abilities of MNs were revealed. Containing the lowest amount of HPMC in its formulation, H901P2-L showed the fastest dissolving ability, which was related to the high amount of lidocaine HCl released through the skin. Moreover, the results of an FTIR analysis showed no chemical interactions among the two polymers and lidocaine HCl. As a result, HPMC/PVP K90 dissolving microneedles can be used to deliver lidocaine HCl through the skin, resulting in a faster onset of anesthetic action.

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Section: Resultsmentioning

confidence: 99%

HPMC/PVP K90 Dissolving Microneedles Fabricated from 3D-Printed Master Molds: Impact on Microneedle Morphology, Mechanical Strength, and Topical Dissolving Property

Chanabodeechalermrung,

Chaiwarit,

Chaichit

et al. 2024

Polymers

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“…In recent years, fractional calculus has been widely used in the research of abnormal diffusion, viscoelastic model, and soft materials [21]. Compared with the integer calculus, fractional calculus can more concisely and accurately describe the physical process with historical memory and spatial correlation [26]. The germination of fractional calculus can be traced back to L' Hospital's letter to Leibniz in 1695.…”

Section: Introductionmentioning

confidence: 99%

Two-Dimensional Electromagnetohydrodynamic (EMHD) Flows of Fractional Viscoelastic Fluids with Electrokinetic Effects

Tian

Zhao

et al. 2022

Nanomaterials

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The present study provides analytical and numerical solutions for an electromagnetohydrodynamic (EMHD) flow using a Caputo time-fractional Maxwell model. The flow is a typical rectangular channel flow. When the scale of the cross-stream is much smaller than the streamwise and spanwise scales, the model is approximated as a two-dimensional slit parallel plate flow. Moreover, the influence of the electric double layer (EDL) at the solid–liquid interface is also considered. The electro-osmotic force generated by the interaction between the electric field and the EDL will induce a flow (i.e., electro-osmotic flow). Due to the application of the electric field at the streamwise and the vertical magnetic field, the flow is driven by Lorentz force along the spanwise direction. Simultaneously, under the action of the magnetic field, the electro-osmotic flow induces a reverse Lorentz force, which inhibits the electro-osmotic flow. The result shows that resonance behavior can be found in both directions in which the flow is generated. However, compared with the classical Maxwell fluid, the slip velocity and resonance behavior of fractional Maxwell fluid are suppressed. In the spanwise direction, increasing the strength of magnetic field first promotes the slip velocity and resonance behavior, and then suppresses them, while in the streamwise direction, both the electro-osmotic flow and resonance behavior are suppressed with the magnetic field.

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“…Issues related to the practical application of selected rheological models have been the subject of many papers for a long time [5][6][7][8][9][10][11][12][13][14][15][16][17][18]. This is mainly due to the large variety of non-Newtonian fluids (emulsions [5][6][7][8], suspensions [8,9], solutions [10], polymer mixtures [11] etc.…”

Section: Introductionmentioning

confidence: 99%

“…This is mainly due to the large variety of non-Newtonian fluids (emulsions [5][6][7][8], suspensions [8,9], solutions [10], polymer mixtures [11] etc. ), their various properties [11][12][13][14] which often change with parameters of technological process, e.g. temperature [10,11,14,15], flow conditions [7,11,16], mixing intensity [17,18] etc.…”

Section: Introductionmentioning

confidence: 99%

Identification of Rheological Properties of Poly(ethylene Oxide) – Water Solutions

Wójtowicz

Kocewiak

Lipin

2020

IVKKT

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In the paper results of investigations of rheological properties for selected PEO-water solutions are presented. On the basis of measurements, carried out with use of rotational viscosimeter values of shear stresses were determined in the relatively wide range of shear rates. Rheological curves were described by the Ostwald de Waele model (or so-called power-law). The model coefficients such as the fluid consistency coefficient k and the flow behavior index n were determined using Levenberg−Marquardt algorithm for nonlinear estimation. The influence of temperature on properties and behavior examined non-Newtonian fluids was also determined. Results were processed in the curve shift parameter at. Experiments shown a significant effect of poly(ethylene oxide) concentration cPEO on rheological properties of examined solutions. For the lowest concentration (cPEO=1.2%) solutions exhibited properties similar to Newtonian fluids with values of n close to 1. With increasing of PEO concentration in water (cPEO=2.4-4.8%), solutions exhibited properties as non - Newtonian fluids, pseudoplastic, without yield limit. In these cases values of n were below unity and for the highest concentration (cPEO=4.8%) belonged to the range of n=0.5694-0.7536, depending on the temperature. Results of investigations can be used during numerical simulations, design and optimization of industrial equipment, working with fluids of this kind, including mixing vessels, columns or heat exchangers.

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Characterizing the rheological behaviors of non-Newtonian fluid via a viscoelastic component: Fractal dashpot

Cited by 25 publications

References 45 publications

HPMC/PVP K90 Dissolving Microneedles Fabricated from 3D-Printed Master Molds: Impact on Microneedle Morphology, Mechanical Strength, and Topical Dissolving Property

HPMC/PVP K90 Dissolving Microneedles Fabricated from 3D-Printed Master Molds: Impact on Microneedle Morphology, Mechanical Strength, and Topical Dissolving Property

Two-Dimensional Electromagnetohydrodynamic (EMHD) Flows of Fractional Viscoelastic Fluids with Electrokinetic Effects

Identification of Rheological Properties of Poly(ethylene Oxide) – Water Solutions

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