Charakterystyka epidemiologiczno-kliniczna 705 nowotworów gruczołów ślinowych

Abstract

In the analyzed group of 699 patients with 705 salivary glands tumors women predominated, consisting 54,2% of all group. The average age in group of malignant tumors was higher than in nonmalignant group. The risk of malignant neoplasms development increased with patient age. In the analyzed group of 705 salivary glands tumors the nonmalignant neoplasms dominated-78,3%. Out of all cases, 547 (77,6%) were localized in the parotid gland, 80 (11,3%) in submandibular gland and 78 (11,1%) in minor salivary glands. Nonmalignant tumors were more frequent in the parotid gland (82,8%) and submandibular gland (71,3%), whereas in minor salivary glands nonmalignant and malignant neoplasms the occurrence was nearly the same. In general-the smaller the salivary gland, the risk of development malignant tumors was higher. In group of nonmalignant salivary gland tumors two histopathological types dominated - pleomorphic adenoma and Warthin's tumor, which comprised 91,8% of the whole group. In the group of 153 malignant salivary gland tumors the most common histopathology were - adenoid cystic carcinoma, mucoepidermoid carcinoma and adenocarcinoma. In the analyzed period of 20 years' time, the incidence of salivary glands tumors increased with high siginificance, both for nonmalignant, as well malignant tumors.

Salivary gland cancer — epidemiology

“…Less frequently the neoplasms are situated in small salivary glands (6-11%) [1,10,14,20]. These data are in accordance with analyses from other countries.…”

“…Less common is lymphoma (about 10%) and squamous cell carcinoma (6-14%). As we mentioned before, the percentage of female and male patients with salivary gland neoplasms is similar, whereby among patients with non-malignant neoplasms there is a slight prevalence of women [1,20]. Studies based on data coming from care units operating salivary gland neoplasms show that the average age for benign neoplasms is about 10 years lower than for malignant neoplasms (50 and 60 years of age respectively).…”

“…The incidence of the former was, according to different authors, 63-75% and of the latter -23.5-29% [1,14,20]. In the case of malignant neoplasms, the most common is epitheliomaadenoidescysticum (23-25%), mucoepidermoid carcinoma (14-27%) and adenocarcinoma (14-22%).…”

“…Similarly, among women the majority of new cases of salivary gland cancer in the recent years of 2010-2014 concerned patients over after 85 years of age (the raw factor 2.5 was for the parotid gland and 1.23 for the remaining salivary glands) [10]. Population studies in laryngological care units point to the highest morbidity in the 50-65 age bracket, which probably results from the highest percentage of patients qualifying for surgery in this age group and not from the real number of patients [1,14,20].…”

Giant pleomorphic adenoma of nasal cavities and paranasal sinuses

“…There is general agreement that the smaller the salivary gland, the more likely it is that the tumor developing therein will be malignant [20]. Benign tumors dominate among tumors of the major salivary glands; malignant tumors constitute 15-32% of parotid gland tumors and 41-45% of submandibular gland tumors.…”