Charcot stage 0: A review and consideratons for making the correct diagnosis early

Holmes, Crystal M.; Schmidt, Brian M.; Munson, Michael; Wrobel, James S.

doi:10.1186/s40842-015-0018-0

Cited by 29 publications

(16 citation statements)

References 46 publications

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“…Stage 0 is the ideal stage for early diagnose of a Charcot foot, but also the most difficult one for the clinician: the patients typically present with a red, swollen, warm foot, but no visible changes (yet) on radiographs. Typical differential diagnoses in this early stage include deep vein thrombosis, gout, osteoarthritis, and infection (cellulitis/osteomyelitis) [10].…”

Section: Introductionmentioning

confidence: 99%

The Charcot foot: a pictorial review

Rosskopf

Loupatatzis²,

Pfirrmann

et al. 2019

Insights Imaging

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Charcot foot refers to an inflammatory pedal disease based on polyneuropathy; the detailed pathomechanism of the disease is still unclear. Since the most common cause of polyneuropathy in industrialized countries is diabetes mellitus, the prevalence in this risk group is very high, up to 35%. Patients with Charcot foot typically present in their fifties or sixties and most of them have had diabetes mellitus for at least 10 years. If left untreated, the disease leads to massive foot deformation. This review discusses the typical course of Charcot foot disease including radiographic and MR imaging findings for diagnosis, treatment, and detection of complications.

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Section: Introductionmentioning

confidence: 99%

The Charcot foot: a pictorial review

Rosskopf

Loupatatzis²,

Pfirrmann

et al. 2019

Insights Imaging

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“…Charcot neuroarthropathy is a devastating condition. Its treatment is complicated by its rarity, 19 misdiagnosis, delayed diagnosis, 3,5 and lack of established foot care. 19,20 Further compounding care for these patients is the presence of a Charcot-related foot ulcer.…”

Section: Discussionmentioning

confidence: 99%

Influence of Patient Setting and Dedicated Limb Salvage Efforts on Outcomes in Charcot-Related Foot Ulcer

Schmidt

Holmes

2019

The International Journal of Lower Extremity Wounds

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Charcot neuroarthropathy is a devastating consequence of diabetes mellitus and peripheral neuropathy. Because of its rarity, the condition is often misdiagnosed or poorly managed. When misadventure occurs, patients with Charcot neuroarthropathy can suffer ulceration, infection, amputation, and death. When patients have Charcot-related foot ulcers, the risks are amplified. Utilizing advanced electronic medical record analysis, a 30-month investigation was undertaken to determine if patients with diabetes mellitus and a concomitant diagnosis of Charcot-related foot ulcer were at greater risk of complications because of location setting of initial treatment for their condition. Charcot foot–related ulcers that are diagnosed in the outpatient setting had established foot specialist care. The outpatient management of the condition lead to a significant reduction in the amount of admissions to a higher acuity setting. However, patient outcomes did not vary once established and dedicated limb salvage efforts were employed. In this large contemporary population managed in a tertiary health system, patients with Charcot-related foot ulcer had negative outcomes when they were initially treated in an inpatient setting and had a significantly greater likelihood of readmission as compared with individuals who had established focused limb salvage care.

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“…This suggests that preexisting diabetes-related deformities could be an etiologic factor. Charcot neuroarthropathy has been diagnosed in 4.6 % of SPK recipients during the first year posttransplantation [ 87 , 88 ]. In addition, a variety of other anatomic sites are affected [ 89 ].…”

Section: Bone Diseases Following Pancreas Transplantationmentioning

confidence: 99%

Diabetes and other endocrine-metabolic abnormalities in the long-term follow-up of pancreas transplantation

Lauria

Ribeiro‐Oliveira

2016

Clin Diabetes Endocrinol

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Pancreas transplantation (PTX) has been demonstrated to restore long-term glucose homeostasis beyond what can be achieved by intensive insulin therapy or islet transplants. Moreover, PTX has been shown to decrease the progression of the chronic complications of diabetes. However, PTX patients require chronic use of immunosuppressive drugs with potential side effects. The long-term follow-up of PTX patients demands special care regarding metabolic deviations, infectious complications, and chronic rejection. Diabetes and other endocrine metabolic abnormalities following transplantation are common and can increase morbidity and mortality. Previous recipient-related and donor-related factors, as well as other aspects inherent to the transplant, act together in the pathogenesis of those abnormalities. Early recognition of these disturbances is the key to timely treatment; however, adequate tools to achieve this goal are often lacking. In a way, the type of PTX procedure, whether simultaneous pancreas kidney or not, seems to differentially influence the evolution of endocrine and metabolic abnormalities. Further studies are needed to define the best approach for PTX patients. This review will focus on the most common endocrine metabolic disorders seen in the long-term management of PTX: diabetes mellitus, hyperlipidemia, and bone loss. The authors here cover each one of these endocrine topics by showing the evaluation as well as proper management in the follow-up after PTX.

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Charcot stage 0: A review and consideratons for making the correct diagnosis early

Cited by 29 publications

References 46 publications

The Charcot foot: a pictorial review

The Charcot foot: a pictorial review

Influence of Patient Setting and Dedicated Limb Salvage Efforts on Outcomes in Charcot-Related Foot Ulcer

Diabetes and other endocrine-metabolic abnormalities in the long-term follow-up of pancreas transplantation

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